Results 201 to 210 of about 263,159 (256)

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Practical Indications and Intraoperative Contribution of Neuroendoscopic Assistance During Exoscopic Skull Base Surgery: A Single-Center Experience. [PDF]

Brain Sci
Matano F, Tsuruya M, Imaoka S, Namatame K, Tomita M, Nounaka Y, Kitamura T, Shirokane K, Umeoka K, Murai Y.   +9 more
europepmc   +1 more source

Capturing Heterogeneous Time‐Variation in Covariate Effects in Non‐Proportional Hazard Regression Models

Biometrical Journal, Volume 68, Issue 5, October 2026.
ABSTRACT A central focus in survival analysis is examining how covariates affect survival time. These covariate effects are often found to be either time‐varying, heterogeneous—such as being specific to patients, treatments, or subgroups—or exhibit both characteristics simultaneously. While the standard model, the Cox proportional hazards model, allows
Niklas Hagemann, Thomas Kneib, Kathrin Möllenhoff   +2 more
wiley   +1 more source

Optic nerve hypoplasia - Clinical profile and co-relation with vision and neuro-radiological features. [PDF]

Indian J Ophthalmol
Kulkarni S, Nalawade R, Bhate M.
europepmc   +1 more source

Pan‐Cancer Analysis of the Immunomodulatory Roles and Prognostic Value of PDXP and Experimental Verification in SKCM

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Multiple public databases, including TCGA, GEO, and TARGET, were utilized to comprehensively analyze pyridoxal phosphatase (PDXP) expression profiles across 34 cancer types. We further explored the associations of PDXP expression with clinicopathological features, tumor immune microenvironment, genomic heterogeneity, functional signaling ...
Yingjian Hu, Xinzhu Zeng, Wei Cao, Jianhao Jiao, Yuan Zhao, Jun Wang   +5 more
wiley   +1 more source

Shining a light on brain tumors: a review of Raman spectroscopy in the operating room. [PDF]

J Biomed Opt
Cutfield S, Ember K, Turner C, Correia J, Petrecca K, Nieuwoudt M, Dragunow M, Aguergaray C, Leblond F.   +8 more
europepmc   +1 more source

Integrating Multimodal MRI Habitat and Transformer‐Based Pathomics to Predict High‐Risk Molecular Subtypes and Explore Biological Mechanisms in Adult Diffuse Gliomas

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Based on the 2021 WHO CNS5 guidelines, this study introduces an integrated high‐risk molecular classification for gliomas and constructs a predictive model by combining multimodal MRI habitat imaging, Transformer‐based WSI pathomics, and clinical information.
Wenju Niu, Xin Duan, Xuan Li, Zehui Li, Qian Liang, Xiangli Yang, Yan Tan, Xiaochun Wang, Guoqiang Yang, Hui Zhang   +9 more
wiley   +1 more source

Apoptin‐Derived Peptide Alleviates Temporal Lobe Epilepsy (TLE) by Limiting Neuronal Ca2+ Overload Through the HSPA1A–AP2B1 Axis

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Epileptogenic stress upregulates HSPA1A, impairs AP2B1 O‐GlcNAcylation and stability, and promotes GluA2 loss‐associated CP‐AMPAR formation and Ca2+ overload. B9 attenuates epileptogenesis by targeting the HSPA1A–AP2B1 axis, restoring AP2B1 O‐GlcNAcylation and stability, preserving GluA2‐associated AMPAR regulation, and reducing pathological Ca2 ...
Zixiao Tan, Qilong Zhai, Jingwen Cui, Xiaoying Gao, Xingan Liu, Zhijie Fan, Yu Liu, Jiahang Sun   +7 more
wiley   +1 more source

A third ventricular floor-associated TTF-1-positive posterior pituitary tumor: illustrative case. [PDF]

J Neurosurg Case Lessons
Zhang Z, Wang B, Wu X, Zhao H, Guan W, Zhang Y, Tang Y, Li S.   +7 more
europepmc   +1 more source

Lactate metabolism and protein lactylation in programmed cell death: From novel mechanism to therapeutic strategies in human diseases

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
This review highlights protein lactylation as a metabolic‐epigenetic regulator linking lactate reprogramming to programmed cell death. By modulating histone and non‐histone targets, lactylation reshapes cell fate decisions and represents a promising biomarker and therapeutic target in human diseases.
Yue Chen, Xiwen Wang, Xiuping Wang, Na Lin, Wenjie Wang, Ruiqi Fu, Yutong Wu, Yi Liu, Hengwei Liu   +8 more
wiley   +1 more source