Results 111 to 120 of about 1,103,257 (330)

Network Localization of Fatigue in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo   +12 more
wiley   +1 more source

Mechanisms of secondary degeneration after partial optic nerve transection

open access: yesNeural Regeneration Research, 2014
Secondary degeneration occurs commonly in the central nervous system after traumatic injuries and following acute and chronic diseases, including glaucoma.
Hong-Ying Li   +4 more
semanticscholar   +1 more source

Edema and features of optic nerve architecture in inflammatory and ischemic neuropathies. Clinical cases

open access: yesJournal of Ophthalmology
Purpose. To describe clinical cases of optic nerve edema in inflammatory and ischemic neuropathies and features of optic disc architecture revealed by optical coherence tomography. Methods. 4 patients were examined.
N. M. Moyseyenko
doaj   +1 more source

POSSIBILITIES OF MODERN IMAGING TECHNIQUES IN DIAGNOSTICS OF OPTIC NERVE DRUSEN (LITERATURE REVIEW)

open access: yesActa Biomedica Scientifica, 2016
With the introduction and development of new diagnostic techniques, the relevance of drusen of the optic nerve diagnostics is increasing. Existing imaging techniques alone or in their various combinations cannot allow to confirm optic nerve drusen in all
E. E. Ioyleva   +2 more
doaj   +1 more source

Differential Activation of Glioprotective Intracellular Signaling Pathways in Primary Optic Nerve Head Astrocytes after Treatment with Different Classes of Antioxidants [PDF]

open access: gold, 2020
Anita K. Ghosh   +7 more
openalex   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu   +5 more
wiley   +1 more source

Microscopic details of age related changes in rat optic nerve

open access: yesSenses and Sciences, 2014
Background: Age-related changes in the number and density of optic nerve fibres were studied in 12-month-old (adult) and 24-month-old (aged) male Wistar rats.
Fernanda Pacella   +5 more
doaj   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin   +2 more
wiley   +1 more source

Hemangioblastoma of the optic nerve

open access: yesHuman Pathology, 1994
A 43-year-old woman presented with progressive loss of vision in the right eye. Magnetic resonance imaging (MRI) showed a prominently enhancing lesion of the optic nerve, thought preoperatively to represent an optic nerve meningioma or optic neuritis. Histological examination of the excised tumor showed this lesion to be hemangioblastoma.
A, Rubio   +4 more
openaire   +2 more sources

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma   +5 more
wiley   +1 more source

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