Results 131 to 140 of about 1,261,152 (360)

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

Optic Nerve Head Parameters, Retinal Nerve Fiber Layer and Executive Functions in Children with Attention Deficit Hyperactivity Disorder [PDF]

open access: yes
Aim: This study aimed to evaluate the relationship between executive functions and optic nerve head parameters (the disc area, the neuroretinal rim volume and cup-to-disc ratio) and peripapillary retinal nerve fiber layer (pRNFL) in medication-free ...
Ali ÇAKIR   +5 more
core   +1 more source

Sheath-Preserving Complete Optic Nerve Avulsion Following Closed-Globe Injury: A Case Report [PDF]

open access: yes, 1994
A 29-year-old man presented with a sudden loss of vision after a closed-globe injury. At presentation, he had no light perception in the right eye and the right pupil was dilated and nonreactive to light.
Onur Furundaoturan   +10 more
core   +1 more source

Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier   +3 more
wiley   +1 more source

Dural ectasia of the optic nerve sheath: is it always benign? [PDF]

open access: yes, 2009
Berker Bakbak1, Hava Dönmez2, Tülay Kansu3, Hayyam Kiratli41Hacettepe University Institute of Neurological Sciences and Psychiatry, Neuro-ophthalmology Unit, Ankara, Turkey; 2Diskapi Yildirim Beyazid Education and Research Hospital ...
Tülay Kansu   +3 more
core  

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process [PDF]

open access: yes, 2014
Glaucoma is characterized by irreversible optic nerve degeneration and is the most frequent cause of irreversible blindness worldwide. Here, the International Glaucoma Genetics Consortium conducts a meta-analysis of genome-wide association studies of ...
Springelkamp, H   +667 more
core   +1 more source

Neuro-sarcoidosis with isolated optic neuropathy: unmasking the chameleon

open access: yesThe Egyptian Journal of Internal Medicine
Isolated optic nerve involvement is rare in sarcoidosis. We report three cases describing atypical clinical and radiological features of isolated optic nerve involvement in sarcoidosis to expand the spectrum of neuro-ophthalmic sarcoidosis.
Shreyashi Jha   +2 more
doaj   +1 more source

Stem Cell Transplantation in Friedreich Ataxia: Cure for Leukemia but No Effect on Neurological Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Friedreich Ataxia (FRDA) is a neurodegenerative disorder of children and young adults associated with cardiomyopathy and other systemic complications. We report a 10‐year‐old girl who presented simultaneously with Acute Myelogenous Leukemia and FRDA who was successfully treated for her leukemia with allogeneic hematopoietic stem cell ...
Alexandra Gitman   +5 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Optic Nerve and Optic Nerve Sheath Biopsy Indications and Outcomes [PDF]

open access: yes
Optic nerve and nerve sheath biopsy (ONB/ONSB) are diagnostic tests considered for optic nerve disease when other investigations have failed to provide a diagnosis.
Reilly Coombs; John Chen; Diva Salomao; Deena Tajfirouz; Eric Eggenberger; Marie DiNome; Jacqueline Leavitt; Misha Pless; James Garrity; Sasha Mansukhani
core  

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