Results 31 to 40 of about 137,284 (347)

Microscopic Inner Retinal Hyper-reflective Phenotypes in Retinal and Neurologic Disease [PDF]

open access: yes, 2014
Purpose. We surveyed inner retinal microscopic features in retinal and neurologic disease using a reflectance confocal adaptive optics scanning light ophthalmoscope (AOSLO). Methods. Inner retinal images from 101 subjects affected by one of 38 retinal or
Carroll, Joseph   +9 more
core   +2 more sources

Magnetic resonance imaging indicator of the causes of optic neuropathy in IgG4-related ophthalmic disease

open access: yesBMC Medical Imaging, 2019
Background The following study investigates the involvement of optic neuropathy in IgG4-related ophthalmic diseases (IgG4-ROD) based on the magnetic resonance imaging (MRI) data, and different imaging features of IgG4-ROD related optic neuropathy related
Jing Li   +5 more
doaj   +1 more source

Role of Oxidative Stress in Ocular Diseases Associated with Retinal Ganglion Cells Degeneration

open access: yesAntioxidants, 2021
Ocular diseases associated with retinal ganglion cell (RGC) degeneration is the most common neurodegenerative disorder that causes irreversible blindness worldwide. It is characterized by visual field defects and progressive optic nerve atrophy.
Eugene Yu-Chuan Kang   +6 more
doaj   +1 more source

Distribution of choline acetyltransferase (ChAT) immunoreactivity in the brain of the teleost cyprinus carpio [PDF]

open access: yes, 2018
Cholinergic systems play a role in basic cerebral functions and its dysfunction is associated with deficit in neurodegenerative disease. Mechanisms involved in human brain diseases, are often approached by using fish models, especially cyprinids, given ...
Casini, Arianna   +3 more
core   +2 more sources

Pharmacogenetics of ophthalmic topical β-blockers [PDF]

open access: yes, 2008
Glaucoma is the second leading cause of blindness worldwide. The primary glaucoma risk factor is elevated intraocular pressure. Topical β-blockers are affordable and widely used to lower intraocular pressure.
McCarty, Catherine A.   +4 more
core   +1 more source

Tempol improves optic nerve histopathology and ultrastructures in cisplatin-induced optic neuropathy in rats by targeting oxidative stress—Endoplasmic reticulum stress—Autophagy signaling pathways

open access: yesFrontiers in Cellular Neuroscience, 2023
IntroductionOptic neuropathy is an affection of the optic neurons, which ends with blindness and occurs either primarily due to direct affection of the optic nerve or secondarily as a complication of chronic diseases and/or adverse effects of their ...
Amira Ebrahim Alsemeh   +10 more
doaj   +1 more source

Visual loss related to macular subretinal fluid and cystoid macular edema in HIV-related optic neuropathy [PDF]

open access: yes, 2012
Optic nerve involvement may occur in various infectious diseases, but is rarely reported after infection by the human immunodeficiency virus (HIV). We report the atypical case of a 38-year-old patient in whom the presenting features of HIV infection were
D. Gautier   +3 more
core   +3 more sources

Therapeutic potential of co-enzyme Q10 in retinal diseases [PDF]

open access: yes, 2017
Coenzyme Q10 (CoQ10) plays a critical role in mitochondrial oxidative phosphorylation by serving as an electron carrier in the respiratory electron transport chain.
Marcheggiani, Fabio   +6 more
core   +1 more source

Assessment of optic nerve and optic tract alterations in patients with orbital space-occupying lesions using probabilistic diffusion tractography [PDF]

open access: yesInternational Journal of Ophthalmology, 2019
AIM: To investigate the diffusion changes in both the optic nerve and optic tract in orbital space-occupying lesion patients with decreased visual acuity, and its clinical significance using probabilistic diffusion tractography (PDT).
Chun-Nan Wu   +6 more
doaj   +1 more source

Transcriptomic Differences Between Human Trabecular Meshwork Stem Cells and Trabecular Meshwork Cells Reveal Specific Biomarker Profiles

open access: yesCurrent Issues in Molecular Biology
Glaucoma is a leading cause of irreversible blindness, normally associated with dysfunction and degeneration of the trabecular meshwork (TM) as the primary cause.
Rong Du   +5 more
doaj   +1 more source

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