Results 71 to 80 of about 135,611 (344)
Multi-dataset Training for Medical Image Segmentation as a Service [PDF]
, 2019 Deep Learning tools are widely used for medical image segmentation. The results produced by these techniques depend to a great extent on the data sets used to train the used network.
Civit Balcells, Antón +6 more
core +1 more source
Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco +18 more
wiley +1 more source
Clinical Applications of the Photopic Negative Response to Optic Nerve and Retinal Diseases
Journal of Ophthalmology, 2012 The photopic negative response (PhNR) in response to a brief flash is a negative-going wave following the b-wave of the cone electroretinogram (ERG) that is driven by retinal ganglion cells (RGCs).
Shigeki Machida
doaj +1 more source
The role of ultrasound methods in the assessment of biometric characteristics of the optic nerve
Российский офтальмологический журнал, 2020 The diagnostics of the optic nerve (ON) pathology relies on the results of clinical and instrumental examinations, electrophysiological tests, computer tomography and magnetic resonance imaging.
T. N. Kiseleva +3 more
doaj +1 more source
The human OPA1delTTAG mutation induces premature age-related systemic neurodegeneration in mouse [PDF]
, 2012 Dominant optic atrophy is a rare inherited optic nerve degeneration caused by mutations in the mitochondrial fusion gene OPA1. Recently, the clinical spectrum of dominant optic atrophy has been extended to frequent syndromic forms, exhibiting various ...
A.L. Mausset-Bonnefont +17 more
core +3 more sources
AB1380 ASSESSMENT OF OPTIC NERVE AND MACULA FINDINGS WITH OPTIC COHERENCE ANGIOGRAPHY IN FEMALE PATIENTS WITH FIBROMYALGIA AND ITS RELATION WITH DISEASE SEVERITY [PDF]
, 2023 Şebnem Koldaş Doğan +4 more
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich +10 more
wiley +1 more source
Toward Non-Invasive Electrical Stimulation for Guided Optic Nerve Regeneration
IEEE Transactions on Neural Systems and Rehabilitation EngineeringThe optic nerve plays a critical role in visual information processing by relaying signals from the retina to the brain. Diseases affecting the optic nerve, such as glaucoma, can severely impair vision due to the nerve’s limited capacity for self ...
Pooyan Pahlavan +9 more
doaj +1 more source
Experimental and Molecular Medicine, 2019 Eye disease: switching signals for repairing injured optic nerves Regulating molecular signaling pathways that control the degradation of cellular components—a process known as autophagy—could offer a new approach to treating optic nerve damage after ...
Yao-Tseng Wen +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann +6 more
wiley +1 more source