Results 211 to 220 of about 1,830,086 (308)

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

Advanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng, Jianhua Wang, Tao Zhang, Xiaofan Fan, Jinxiu Guo, Shiyuan Zhao, Wenxue Sun, Pei Jiang   +7 more
wiley   +1 more source

Structure-Function Relationship Between Optic Nerve Head Morphometry and Virtual Reality-Based Perimetry in Open-Angle Glaucoma. [PDF]

Transl Vis Sci Technol
Lüke JN, Poell C, Lüke V, Enders P, Dietlein T, Lappa A, Schrittenlocher S.   +6 more
europepmc   +1 more source

ReLink: Reliable Deep Learning for Microscopic Motion Tracking

Advanced Science, EarlyView.
ReLink enables reliable trajectory linking in single‐particle tracking by integrating physics‐informed motion statistics with confidence‐based adaptive filtering. Across diverse simulated and experimental conditions, ReLink robustly reconstructs trajectories and preserves the fidelity of downstream analyses, enabling accurate characterization of ...
Yuan Jiang, Xiaochen Feng, Hongda Wei, Hao Sha, Hongpeng Wang, Min Zhang, Sanyang Han, Yongbing Zhang   +7 more
wiley   +1 more source

Optic Nerve Head Microvascular Changes Associated with Intracranial Aneurysms. [PDF]

Beyoglu Eye J
Buyuktepe TC, Buyuktepe M, Kiziltunc PB, Eroglu U, Dogan I, Atilla H.   +5 more
europepmc   +1 more source

Loss of Lepr in Fibroblasts Drives Tumor Development by Promoting Macrophage Infiltration

Advanced Science, EarlyView.
TNFα and TGFβ signaling reprograms Lepr+ fibroblasts toward a LeprnegMmphigh inflammatory CAF (iCAF) state, with downregulation of the Tcf21‐Lepr axis contributing to this transition. Lepr loss induces Csf3, which contributes to the enhanced macrophage‐recruiting capacity of these iCAFs, thereby promoting tumor development. Thus, inflammatory signaling
Manyu Song, Wuqi Yang, Bangran Qi, Liyuan Hou, Xu Yang, Jiuzhi Xu, Shengyuan Tian, Shuiling Jin, Lu Yu, Zhengquan Yu, Min Deng, Jiaqiang Huang, Suoqin Jin, Cong Lv   +13 more
wiley   +1 more source

Vitreopapillary Traction Causing Optic Nerve Head Elevation. [PDF]

Case Rep Ophthalmol Med
Khodeiry MM, Ayoubi M, Dorizas CA, Mendoza-Santiesteban CE, Kostic M.   +4 more
europepmc   +1 more source

Clinical utility of pharyngeal high‐resolution manometry with impedance for upper esophageal sphincter dysfunction in gastroenterology

Advances in Digestive Medicine, EarlyView.
Abstract Pharyngeal high‐resolution manometry with impedance (P‐HRM‐I) is an established assessment method used to evaluate pharyngeal swallowing. It provides precise quantification of swallowing biomechanics that enable the detection of alterations in swallowing physiology.
Mistyka Schar, Taher Omari, Michal Szczesniak, Chien‐Lin Chen, Richard Heddle, Charles Cock   +5 more
wiley   +1 more source

Exploring Structural and Vascular Changes of the Optic Nerve Head After Trabeculectomy in Primary Open-Angle Glaucoma. [PDF]

Vision (Basel)
Cappellani F, Castellino N, Zeppieri M, D'Esposito F, Avitabile A, Rubegni G, Cannizzaro L, Gagliano G, Longo A.   +8 more
europepmc   +1 more source

Patient‐Mounted Neuro Optical Coherence Tomography for Targeted Minimally Invasive Micro‐Resolution Volumetric Imaging in Brain In Vivo

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu, Zhiwei Fang, Huxin Gao, Tinghua Zhang, Tao Zhang, Peng Liu, Hongliang Ren, Wu Yuan   +7 more
wiley   +1 more source

Case Report: Bilateral optic nerve head masses and retinopathy in a patient with B-cell acute lymphoblastic leukemia receiving CAR T-cell therapy masquerading as fungal endophthalmitis. [PDF]

Front Immunol
Heng JS, Ramos-Davila E, Maiz AM, Henderson A, Eberhart CG, Liberman P, Métais JY, Gottschalk S, Schratz KE, Symons H, Bonifant CL, Handa JT.   +11 more
europepmc   +1 more source