Results 11 to 20 of about 85,145 (254)

Whole genome sequencing unveils genetic heterogeneity in optic nerve hypoplasia. [PDF]

PLoS ONE, 2020
Optic nerve hypoplasia (ONH) is a congenital malformation with a reduced number of retinal ganglion cell axons in a thin optic nerve. It is a common cause of visual impairment in children and ONH is associated with neurodevelopmental disorders, pituitary
Sara Dahl, Maria Pettersson, Jesper Eisfeldt, Anna Katharina Schröder, Ronny Wickström, Kristina Teär Fahnehjelm, Britt-Marie Anderlid, Anna Lindstrand   +7 more
doaj   +3 more sources

Association of prepregnancy body mass index and gestational weight gain on severity of optic nerve hypoplasia [PDF]

Birth Defects Research, 2023
Optic nerve hypoplasia (ONH) is a birth defect of unknown etiology and a leading cause of visual impairment in developed countries. Recent studies suggest that factors of deprivation and exposures of poor nutritional status, such as lower gestational ...
Betty A Situ
exaly   +3 more sources

Automated Retinal Image Analysis to Detect Optic Nerve Hypoplasia [PDF]

Information Technology and Control
Identification of the optic disc and fovea is crucial for automating the diagnosis and screening of retinal diseases. Based on quantitative calculations, this study presents a decision support system for doctors that automatically detect optic nerve ...
Çelik, Canan, Yücadag, İbrahim, Akcam, Hanife Tuba, Yucedag, Ibrahim   +3 more
core   +2 more sources

Incidental bilateral optic nerve hypoplasia. [PDF]

BMJ Case Rep, 2017
A 19-year-old man was incidentally noted to have a bitemporal heteronymous hemianopia on automated perimetry during his first optician’s sight test (figure 1). The patient reported life-long reduced vision in the right eye although this was his first presentation to ophthalmic services.
Harvey JP.
europepmc   +4 more sources

Optic nerve head analysis of superior segmental optic hypoplasia using Heidelberg retina tomography

Clinical Ophthalmology, 2010
Atsushi Miki1,2, Motohiro Shirakashi1, Kiyoshi Yaoeda1, Atsushi Fukushima1, Mineo Takagi1, Haruki Abe11Division of Ophthalmology and Visual Sciences, Niigata University Graduate School of Medical and Dental Sciences, Niigata, 2Department of Ophthalmology,
Atsushi Miki, Motohiro Shirakashi, Kiyoshi Yaoeda, et al   +3 more
doaj   +1 more source

Pseudo-Foster Kennedy Syndrome due to unilateral optic nerve hypoplasia: a case report

Journal of Medical Case Reports, 2008
Introduction Pseudo-Foster Kennedy Syndrome is described as unilateral optic disc swelling with contralateral optic atrophy in the absence of an intracranial mass causing compression of the optic nerve.
Bansal Shveta, Dabbs Timothy, Long Vernon   +2 more
doaj   +2 more sources

OPTIC NERVE HYPOPLASIA: CHANGING PERSPECTIVES [PDF]

Australian and New Zealand Journal of Ophthalmology, 1986
AbstractOptic nerve hypoplasia, having once been regarded as exceedingly rare, is now regarded as one of the major causes of visual loss in infancy. Recognition of subtle forms and segmental forms of optic nerve hypoplasia are important in explaining the evaluation of subnormal vision.
Creig S Hoyt, Frank A Billson
exaly   +3 more sources

High-Resolution Imaging of the Optic Nerve and Retina in Optic Nerve Hypoplasia

Ophthalmology, 2015
Purpose To investigate the optic nerve and macular morphology in patients with optic nerve hypoplasia (ONH) using spectral-domain optical coherence tomography (SD OCT). Design Prospective, cross-sectional, observational study.
Anastasia Pilat, Rebecca J Mclean, Frank A Proudlock   +2 more
exaly   +3 more sources

Managing elevated intraocular pressure in a patient with optic nerve hypoplasia

Clinical Optometry, 2009
Karina Marcovitch, Joseph SowkaNova Southeastern University, College of Optometry, Davie, FL, USABackground: Optic nerve hypoplasia (ONH) is a congenital optic disc anomaly, often manifesting with visual deficits.Case: A 51-year-old woman with a history ...
Karina Marcovitch, Joseph Sowka
doaj   +1 more source

Genetic causes of optic nerve hypoplasia [PDF]

Journal of Medical Genetics, 2017
Optic nerve hypoplasia (ONH) is the most common congenital optic nerve anomaly and a leading cause of blindness in the USA. Although most cases of ONH occur as isolated cases within their respective families, the advancement in molecular diagnostic technology has made us realise that a substantial fraction of cases has identifiable genetic causes ...
Chen, Chun-An, Yin, Jiani, Lewis, Richard Alan, Schaaf, Christian P.   +3 more
openaire   +4 more sources