Results 61 to 70 of about 7,387 (178)

An Implanted Tooth That Can Feel

Advanced Science, Volume 13, Issue 32, 9 June 2026.
To endow the implanted tooth with masticatory perception, herein we demonstrate that a 3D‐printed piezoelectric‐core/robust‐sheath implanted tooth can rebuild the sensing feedback, serving as “mechanoreceptors” in converting the mechanical chewing force to electrical signals, and up to brain through surrounding alveolar nerve system.
Yaru Cao, Zhenhua Wu, Jiwei Sun, Ke Song, Jiayi Li, Yujin Li, Wenqi Chen, Hanyu Li, Shue Li, Cheng Yang, Silin Liu, Yunyun Han, Bin Su, Yumei Ding   +13 more
wiley   +1 more source

Channel Dysfunction as the Basis for Comorbidities in Multiple Sclerosis and Depression

Archiv der Pharmazie, Volume 359, Issue 6, June 2026.
Ion channel remodelling induced by neuroinflammation in multiple sclerosis alters neuronal excitability and immune signalling, creating shared molecular pathways that link multiple sclerosis pathology to depression and reveal novel pharmacological targets.
Nicole Rychlik, Kay Jüngling, Sven G. Meuth, Thomas Budde, Marta Méndez‐Couz   +4 more
wiley   +1 more source

Evaluating Anesthetics for Improving Scientific Research and Welfare Using Larval Zebrafish

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Using physiological and behavioral assays, we quantified the effectiveness and appropriateness of six commonly used fish anesthetics on zebrafish embryos. Different anesthetics performed better under different contexts. Figure prepared using BioRender.com.
Sylvia Dimitriadou, Mhairi Miller, Ali Pilehvar, Lynne U. Sneddon, Jessica L. Bamsey, Damilola Hogan‐Bassey, Maciej Trznadel, Jonathan S. Ball, Aya Takesono, Courtney Hillman, Hannah Rickard, Grace Popplewell, Jenna Corcoran, Tetsuhiro Kudoh, Charles R. Tyler, Matthew J. Winter   +15 more
wiley   +1 more source

RXR Gamma Enables Oligodendrocyte Differentiation by Suppressing Sonic Hedgehog Signaling

Glia, Volume 74, Issue 6, June 2026.
Using pharmacogenetic approaches, Baldassarro et al. demonstrate that RXRγ suppresses the SHH signaling pathway in OPCs to ensure their efficient differentiation following T3 stimulation. Accordingly, Rxrg−/− OPCs displayed compromised differentiation which was normalized by the pharmacological inhibition of the hyperactive SHH pathway.
Vito Antonio Baldassarro, Quentin Brassart, Valérie Fraulob, Laura Calzà, Wojciech Krezel   +4 more
wiley   +1 more source

Beyond intracranial pressure: Cerebrospinal fluid compartmentalization in spaceflight‐associated neuro‐ocular syndrome

Experimental Physiology, EarlyView.
Susan P. Mollan, Damian M. Bailey
wiley   +1 more source

Developmental Profiling of Structural and Functional Maturation in Mouse Corpus Callosum

Glia, Volume 74, Issue 6, June 2026.
Progressive myelin development in mouse corpus callosum is accompanied by gradual decrease in oligodendrocyte precursor cell density and increase in oligodendrocyte density. Pro‐Capase‐3 is transiently upregulated in oligodendrocyte during postnatal development.
Hayes Johnson, Maren Beall, Sophia Latifi, Juan Peng, Wenjing Sun   +4 more
wiley   +1 more source

Lifespan Trajectories of Asymmetry in White Matter Tracts

Human Brain Mapping, Volume 47, Issue 8, June 1, 2026.
(A) Large‐scale lifespan modeling of white matter asymmetry. Diffusion MRI data from 35,000+ individuals (0‐100 years) across 50 cohorts were used to generate normative lifespan trajectories of white matter asymmetry. Thirty bilateral tracts were segmented, and microstructural (FA, MD, AD, RD) and macrostructural (volume, length) features were ...
Sam Bogdanov, Praitayini Kanakaraj, Michael E. Kim, Jessica Samir, Chenyu Gao, Karthik Ramadass, Gaurav Rudravaram, Nancy R. Newlin, Derek Archer, Timothy J. Hohman, Angela L. Jefferson, Victoria L. Morgan, Alexandra Roche, Dario J. Englot, Susan M. Resnick, Lori L. Beason Held, Laurie E. Cutting, Laura A. Barquero, Micah A. D'Archangel, Tin Q. Nguyen, Kathryn L. Humphreys, Yanbin Niu, Sophia Vinci‐Booher, Carissa J. Cascio, The HABS‐HD Study Team, Alzheimer's Disease Neuroimaging Initiative, The BIOCARD Study Team, Sid E O'Bryant, Kristine Yaffe, Arthur Toga, Robert Rissman, Leigh Johnson, Meredith Braskie, Kevin King, James R Hall, Melissa Petersen, Raymond Palmer, Robert Barber, Yonggang Shi, Fan Zhang, Rajesh Nandy, Roderick McColl, David Mason, Bradley Christian, Nicole Phillips, Stephanie Large, Joe Lee, Badri Vardarajan, Monica Rivera Mindt, Amrita Cheema, Lisa Barnes, Mark Mapstone, Annie Cohen, Amy Kind, Ozioma Okonkwo, Raul Vintimilla, Zhengyang Zhou, Michael Donohue, Rema Raman, Matthew Borzage, Michelle Mielke, Beau Ances, Ganesh Babulal, Jorge Llibre‐Guerra, Carl Hill, Rocky Vig, Zhiyuan Li, Simon N. Vandekar, Panpan Zhang, John C. Gore, Stephanie J. Forkel, Bennett A. Landman, Kurt G. Schilling   +72 more
wiley   +1 more source

Engineered Pericyte‐Targeted Extracellular Vesicles Protect Against Hypoperfusion‐Induced Cognitive Impairment and Vascular Demyelination

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Schematic illustration on a therapeutic strategy wherein engineered extracellular vesicles (EVs) are delivered intranasally and specifically target pericytes. In a model of chronic cerebral hypoperfusion (BCAS), this targeted approach preserves cerebral blood flow, reinforces blood‐brain barrier (BBB) integrity, stabilizes the neurovascular unit (NVU),
Weiwei Shen, Weishi Liu, Min Guo, Tongyao You, Yingzhe Wang, Tiansiyu Wen, Suzhen Liang, Xiaodi Xie, Yanfeng Jiang, Qiang Dong, Jin‐Tai Yu, Mei Cui   +11 more
wiley   +1 more source

A Multivariate CT‐Based Model for Differentiating Styloid Syndrome From Asymptomatic Styloid Elongation: A Retrospective Comparative Study of Positional and Morphological Parameters

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
ABSTRACT Objective To compare computed tomography positional and morphological parameters between patients with styloid syndrome and individuals with asymptomatic styloid elongation. Methods A retrospective study of 151 patients with styloid syndrome and 162 individuals with asymptomatic styloid elongation was conducted.
Yifan Wang, Zezheng Yang
wiley   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

MedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang, Jingfei Shi, Linlin Xu, Guangrui Zhao, Yue Chen, Lin Cheng, Xiaokang Li, Zhigang Sun, Shuhong Huang   +8 more
wiley   +1 more source