Results 41 to 50 of about 1,889 (150)

Audiological Characteristics in Vestibular Schwannoma Patients

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Vestibular schwannoma (VS) is a benign tumor that originates from the Schwann cells of the vestibular nerve sheath in the internal auditory canal. This retrospective study collected data from patients with VS who underwent surgical treatment to identify their demographic characteristics and audiometric features.
Shan Zeng, Yi‐Yun Lou, Hui‐Qian Yu, Wei‐Dong Zhao, Wen‐Yan Li   +4 more
wiley   +1 more source

Combined endoscopic transethmoid and transconjunctival en bloc resection of optic nerve tumors in patients lacking functional vision

Frontiers in Oncology, 2022
BackgroundSurgical treatment of optic nerve tumors is challenging. The study’s objective was to evaluate the efficacy of a combined endoscopic transethmoid and transconjunctival approach in patients without functional vision.DesignA retrospective ...
Jieliang Shi, Yunhai Tu, Mingna Xu, Wencan Wu   +3 more
doaj   +1 more source

Differentiating neuro-ophthalmic cases from normal tension glaucoma: series case reports and literature review

Yanke Xuebao
[Objective:] To analyze the differentiating manifestations of glaucomatous and non-glaucomatous optic neuropathies using real clinical cases and to enhance the ability to make differential diagnosis.
PAN Xiaohua, YANG Mingmin, TAO Yufei, FENG Yanting, FAN Ning   +4 more
doaj   +1 more source

Results of surgical removal of optic nerve sheath meningioma

Ендоваскулярна нейрорентгенохірургія, 2018
Objective – to study the features of surgical technique and to analyze the results of treatment of patients with optic nerve sheath meningioma (ONSM). Materials and methods. A retrospective analysis of surgical treatment of 8 patients (5 men, 3 women)
MS. Hudym
doaj   +1 more source

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, Volume 13, Issue 26, 8 May 2026.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, Volume 16, Issue 4, Page 803-813, April 2026.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Novel NOTCH3 alteration expanding the molecular spectrum of pericytic tumours: report of two cases

Histopathology, Volume 88, Issue 4, Page 922-927, March 2026.
Introduction Myofibromas are part of the pericytic tumour family, which includes myopericytomas, glomus tumours and angioleiomyomas. While they typically display benign behaviour when arising in the skin and subcutaneous tissues of the head and neck, rare aggressive variants have been reported, particularly those with visceral or intracranial ...
Irena Antonia Ungureanu, Megane Le Quang, Rihab Azmani, Marie Ancelle, Henri Margot, Guillaume Chotard, François Le Loarer, Nathalène Truffaux   +7 more
wiley   +1 more source

Optic Nerve Sheath Meningioma in the First Decade of Life: Case Report and Review of the Literature

Case Reports in Ophthalmology, 2012
Background/Aim: Tumors of the optic nerve are mostly either optic nerve gliomas or optic nerve sheath meningiomas (ONSMs). While gliomas occur in children, most meningiomas are slow-growing tumors affecting middle-aged individuals with progressive visual
Mário L.R. Monteiro, Allan Christian P. Gonçalves, Sheila Aparecida C. Siqueira, Eloísa M.M. Gebrim   +3 more
doaj   +1 more source

Optic Chiasm and Bilateral Optic Nerve Oligodendroglioma in A 29‐Month‐Old German Shepherd

Veterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT Objective To report the first documented case of high‐grade optic chiasm and nerve oligodendroglioma in a young dog and contribute to the comparative study of gliomas in humans and canines. Animal Studied A 29‐month‐old male intact German Shepherd.
Vienna M. Lunking, Rajdeep Multani, Devin Fussell, LaTisha N. Knight, Erin Keenihan, Danielle M. Meritet, Abigail R. Armwood, Annie Oh   +7 more
wiley   +1 more source

Unveiling the Enigma: Optic Nerve Sheath Meningioma Masquerading as Optic Neuritis

TNOA Journal of Ophthalmic Science and Research
A 37-year-old female came with complaints of sudden vision loss in her left eye for the past 4 days along with pain when rotating her eyeball. Vision in her left eye was 6/9. Fundus examination revealed a grade 3 disc edema in the left eye. Visual evoked
Arumugam Balraj, Harini Ravikumar, Neha Sapar   +2 more
doaj   +1 more source