Results 101 to 110 of about 7,956,506 (236)

Neuroprotection in Optic Neuritis: A Clinical Trial

, 2007
Results from the Optic Neuritis Treatment Trial (ONTT) indicate that some degree of persistent visual loss occurs regardless of current therapeutic intervention in acute demyelinating optic neuritis (ON).
Laura J. Balcer
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When Glycaemic Control Comes Too Fast: Treatment‐Induced Neuropathy of Diabetes and Charcot Neuro‐Osteoarthropathy as Emerging Iatrogenic Complications of Rapid Metabolic Correction

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Purpose of Review Diabetes therapeutics can lower glycated haemoglobin (HbA1c) by several percentage points within weeks. While long‐term microvascular risk is reduced by improved glycaemia, abrupt metabolic transitions may destabilise tissues adapted to chronic hyperglycemia.
Dured Dardari
wiley   +1 more source

Visual Field Profile of Optic Neuritis: A Final Follow-Up Report from the Optic Neuritis Treatment Trial (ONTT) from Baseline to 15 Years

, 2010
To evaluate visual field abnormalities after an episode of optic neuritis in Optic Neuritis Treatment Trial (ONTT) patients.IC-H3fi-optic-neuritis-treatment ...
John L. Keltner, MD; Chris A. Johnson, MD; Kimberly Cello; Robin Gal; Roy Beck
core  

Visual field characteristics in neuromyelitis optica in absence of and after one episode of optic neuritis

Clinical Ophthalmology, 2013
Harold Merle,1 Stéphane Olindo,2 Séverine Jeannin,2 Rabih Hage,1 Angélique Donnio,1 Raymond Richer,1 Philippe Cabre2 1Service d'Ophtalmologie, 2Service de Neurologie, Centre Hospitalier Universitaire de Fort de France, Fort-de ...
Merle H, Olindo S, Jeannin S, Hage R, Donnio A, Richer R, Cabre P   +6 more
doaj  

The Prevalence of Neuropathic Pain in Multiple Sclerosis—A Systematic Review and Meta‐Analysis Using the NeuPSIG Algorithm

European Journal of Pain, Volume 30, Issue 8, September 2026.
ABSTRACT Background and Objectives Multiple sclerosis (MS) is a neurodegenerative disorder frequently leading to neuropathic pain. Due to the neurodegenerative nature, the diagnosis of neuropathic pain remains challenging. A grading system has been developed providing an overview of diagnostic certainty (i.e., possible, probable and definite). Since no
Rasmus C. Jungersen, Victor K. Baccaro, Lars G. Hvid, Ulrik Dalgas, Morten Hoegh   +4 more
wiley   +1 more source

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

MedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang, Yin Zhu, Fang Xu, Yongjing Liu, Yuan Li, Ling Yuan, Liqin Wei, Bo Huang, Yan Chen, Pei Huang, Zuochen Du   +10 more
wiley   +1 more source

Subretinal angiostrongyliasis-induced optic neuritis

, 2013
Suthasinee Sinawat,1 Yosanan Yospaiboon,1 Supat Sinawat21Vitreoretinal Unit, Department of Ophthalmology, 2Department of Physiology, Khon Kaen University, Khon Kaen, ThailandAbstract: A 27-year-old Thai male presented with progressive visual loss and a ...
Yospaiboon Y, Sinawat S
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Idiopathic Orbital Inflammation Masquerading as Relapse of Seronegative Juvenile Myasthenia Gravis: A Case Report

Journal of Paediatrics and Child Health, EarlyView.
Wenhao Duan, Yanqing Zhang, Wensha Nie, Hongchao Jiang, Huiping Wang   +4 more
wiley   +1 more source

What is the incidence and clinical significance of dry eye disease in patients treated with immune checkpoint inhibitors? A systematic review and meta‐analysis of ocular immune‐related adverse events

Acta Ophthalmologica, Volume 104, Issue 6, Page e599-e614, September 2026.
Abstract Purpose Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but may cause immune‐related adverse events (irAEs), including dry eye disease (DED). This study aimed to quantify the incidence of ICI‐associated DED and to evaluate factors contributing to variability across studies.
Kai‐Yang Chen, Hoi‐Chun Chan, Chi‐Ming Chan   +2 more
wiley   +1 more source

Optic Neuritis Treatment Trial: An Update

, 1994
I. Relation of optic neuritis to multiple sclerosis II. ONTT entiy criteria, treatment assignment, patient population III. Specifics of included and excluded subjects for long tenn study and nature of follow up exams and analysis IV.
Mark J. Kupersmith
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