Results 21 to 30 of about 45,153 (265)

Ischemic optic neuropathy

open access: yesInternational Ophthalmology, 1978
Ischemic optic neuropathy (ION), based on vascular anatomy of the optic nerve, pathogenesis and clinical picture, consists of two distinct entities: anterior (AION) and posterior (PION) ischemic optic neuropathies. AION is due to interference with posterior ciliary artery supply to the optic nerve head and retrolaminar part of the optic nerve; it ...
openaire   +5 more sources

Our Experience in Endoscopic Transnasal Optic Nerve Decompression

open access: yesBengal Journal of Otolaryngology and Head Neck Surgery
INTRODUCTION: Traumatic optic neuropathy (TON), a severe complication following head injury, affects about 0.5% to 5% of patients with closed head injuries.1 Visual acuity (VA) loss associated with TON can be partial or complete and temporary or ...
Saravana Selvan Velmurugan   +5 more
doaj   +1 more source

Multifocal visual evoked potential in optic neuritis, ischemic optic neuropathy and compressive optic neuropathy

open access: yesIndian Journal of Ophthalmology, 2014
Purpose: To investigate the effect of optic neuritis (ON), ischemic optic neuropathy (ION) and compressive optic neuropathy (CON) on multifocal visual evoked potential (mfVEP) amplitudes and latencies, and to compare the parameters among three optic ...
Manju Jayaraman   +3 more
doaj   +1 more source

To study visual evoked potential in patients with optic nerve diseases

open access: yesJournal of Clinical Ophthalmology and Research
Background: To study Visual Evoked Potential in patients with Optic Nerve diseases. Study design and settings: Cross – Sectional study. Material and Methods: 72 patients were included in our study, aged 12 years and above, diagnosed as optic nerve ...
Kavita Poonia   +3 more
doaj   +1 more source

Uraemic optic neuropathy – a rare presentation of uraemia

open access: yesAfrican Journal of Nephrology, 2018
Uraemic optic neuropathy (UON) is an acute but reversible loss of vision in patients with end-stage renal failure. Hypoperfusion of the posterior ciliary arteries, the major blood supply to the optic nerve head, results in ischaemic injury to the nerve ...
Adaobi Uzoamaka Solarin   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Pseudo Foster Kennedy Syndrome secondary to uncontrolled hypertension and diabetes mellitus: A case report

open access: yesMedical Journal of Dr. D.Y. Patil University, 2014
Pseudo-Foster Kennedy Syndrome is described as unilateral optic disc swelling with contra lateral optic atrophy in the absence of an intracranial mass causing compression of the optic nerve.
Kavita R Bhatnagar   +3 more
doaj   +1 more source

Сhronic relapsing inflammatory optic neuropathy: diagnostic strategies and treatment (literature review)

open access: yesMedičnì Perspektivi, 2023
The article presents a review and analysis of scientific works on the problem of chronic relapsing inflammatory optic neuropathy, its diagnostic criteria and treatment methods.
T.I. Nehrych   +2 more
doaj   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

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