Results 61 to 70 of about 44,099 (219)

Selective diet induced nutritional optic neuropathy in developmentally normal children

American Journal of Ophthalmology Case Reports
Purpose: Nutritional deficiencies in developed countries are a rare but potentially intervenable cause of optic neuropathy in pediatric populations.
Rhea W. Teng, Gena Heidary, Ryan A. Gise
doaj   +1 more source

Magnetic resonance imaging indicator of the causes of optic neuropathy in IgG4-related ophthalmic disease

BMC Medical Imaging, 2019
Background The following study investigates the involvement of optic neuropathy in IgG4-related ophthalmic diseases (IgG4-ROD) based on the magnetic resonance imaging (MRI) data, and different imaging features of IgG4-ROD related optic neuropathy related
Jing Li, Yan Zhang, Hang Zhou, Lei Wang, Zhenchang Wang, Hongyang Li   +5 more
doaj   +1 more source

Diagnostic Odyssey of Atypical Long‐Chain 3‐Hydroxyacyl‐CoA Dehydrogenase Deficiency (LCHADD) Explained by Three Allelic Products From Two Pathogenic Variants

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Long‐chain 3‐hydroxyacyl‐CoA dehydrogenase deficiency (LCHADD) is an autosomal recessive mitochondrial defect of long‐chain fatty acid β‐oxidation, caused by biallelic pathogenic variants in HADHA or HADHB. We report a 22‐year‐old male with an atypically mild presentation of LCHADD who was referred to the Undiagnosed Diseases Network (UDN ...
Yutaka Furuta, Lynette C. Rives, T. Andrew Burrow, Thomas A. Cassini, Rory J. Tinker, Amy K. Robertson, Kimberly M. Ezell, Rizwan Hamid, Joy D. Cogan, John A. Phillips III   +9 more
wiley   +1 more source

Genetic susceptibility to optic neuropathy in patients with alcohol use disorder

Journal of Translational Medicine
Background The pathophysiology of toxico-nutritional optic neuropathies remains debated, with no clear understanding of the respective roles played by the direct alcohol toxicity, smoking and the often associated vitamin deficiencies, which are risk ...
Camille Delibes, Marc Ferré, Marine Rozet, Valérie Desquiret-Dumas, Alexis Descatha, Bénédicte Gohier, Philippe Gohier, Patrizia Amati-Bonneau, Dan Milea, Pascal Reynier   +9 more
doaj   +1 more source

Risk factors for optic neuropathy after clipping for paraclinoid aneurysms: A retrospective study

World Neurosurgery: X
Background: Anterior clinoidectomy (AC) is an important technique for the management of aneurysms in the paraclinoid region. Conventional drill-based AC technique (Drill AC) can cause optic neuropathy. Therefore, starting in July 2017, we transitioned to
Junya Iwama, Hiroki Sato, Seiji Kuribara, Makoto Mizushima, Takumi Hirabayashi, Ryosuke Tsuchiya, Takafumi Shindo, Keisuke Ohnaka, Takanori Hayakawa, Katsumi Takizawa   +9 more
doaj   +1 more source

A Case of Tacrolimus-Induced Posterior Reversible Encephalopathy Syndrome Initially Presenting as a Bilateral Optic Neuropathy

Case Reports in Ophthalmology, 2019
Purpose: To report a case of asymmetric bilateral optic neuropathy in a patient receiving tacrolimus for immunosuppression after kidney transplantation with subsequent stroke-like symptoms of posterior reversible encephalopathy syndrome (PRES).
Sumana S. Kommana, Upneet Bains, Vivian Fasula, Jeffrey Henderer   +3 more
doaj   +1 more source

Psychiatric and Cognitive Features in Italian Women With the FMR1 Premutation: A Comprehensive Assessment Using SCID‐5 and Standardized Cognitive Measures

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Women with the FMR1 premutation (PM) are at increased risk for fragile X‐associated conditions (FXPAC), including cognitive and psychiatric features collectively termed fragile X‐associated neuropsychiatric disorders (FXAND). This study is the first to systematically investigate cognitive and psychiatric features in Italian female premutation ...
Federica Alice Maria Montanaro, Randi J. Hagerman, Giuseppina Spano, Flora Tassone, Giancarlo Logroscino, Andrea Bosco   +5 more
wiley   +1 more source

Why do we need optic nerve decompression of traumatic optic neuropathy patients?

Interdisciplinary Neurosurgery, 2014
Traumatic optic neuropathy can be treated by various methods including high-dose steroids and surgical decompression. Neurosurgical decompression could be required in patients with mechanical compression of the optic nerve by displaced orbital roof ...
Seong Rok Han, M.D., Ph.D.
doaj   +1 more source

Metabolic and biochemical profiling reveals phenotypic heterogeneity in Zucker diabetic fatty rats

Animal Models and Experimental Medicine, EarlyView.
Genetically uniform Zucker Diabetic Fatty (ZDF) rats spontaneously develop four distinct metabolic phenotypes despite identical housing and diet conditions. Each phenotype exhibits unique biomarker signatures encompassing glucose homeostasis, insulin secretion, polyol pathway activation, oxidative stress, inflammatory cytokines, and neurotrophic ...
Marek Lepáček, Pavol Boďo, Barbora Kaločayová, Marta Šoltésová Prnová   +3 more
wiley   +1 more source

Nonarteritic anterior ischemic optic neuropathy: cause, effect, and management

Eye and Brain, 2017
Shauna Berry,1 Weijie V Lin,2 Ama Sadaka,1 Andrew G Lee1–7 1Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, TX, USA; 2Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA; 3Department of
Berry S, Lin WV, Sadaka A, Lee AG
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