Results 41 to 50 of about 661,976 (251)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Migration of Intraocular Silicone Oil into the Optic Tract

open access: yes, 2022
Silicone oil is often used for intraocular endotamponade in vitreoretinal surgery.
Ji Hyae Lee; Marez Megalla; Long Tu; Peter Podany; Adeniyi Fisayo
core  

Age effect on retina and optic disc normal values [PDF]

open access: yes, 2005
Purpose: To investigate retinal thickness and optic disc parameters by the Retinal Thickness Analyzer (RTA) glaucoma program in older normal subjects and to determine any age effect.
Chryssafis, C.   +5 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

Retinal nerve fiber layer loss documented by optical coherence tomography in patients with optic tract lesions Perda da camada de fibras nervosas retinianas documentada pela tomografia por coerência óptica em pacientes com lesões do trato óptico

open access: yesRevista Brasileira de Oftalmologia, 2009
PURPOSE: To report abnormalities of retinal nerve fiber layer (RNFL) thickness using Stratus - optical coherence tomography (OCT) in two patients with optic tract lesions.
Mário Luiz Ribeiro Monteiro   +1 more
doaj   +1 more source

Accurate and reliable segmentation of the optic disc in digital fundus images [PDF]

open access: yes, 2014
We describe a complete pipeline for the detection and accurate automatic segmentation of the optic disc in digital fundus images. This procedure provides separation of vascular information and accurate inpainting of vessel-removed images, symmetry-based ...
Giachetti, Andrea   +4 more
core   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin   +11 more
wiley   +1 more source

Optic disc Pit with Retinoschisis in Non-Arteritic Anterior Ischemic Optic Neuropathy

open access: yes, 2023
This case describes a patient with non-arteritic anterior ischemic optic neuropathy and concurrent macular retinoschisis who was later found to have an optic disc pit after resolution of disc edema.
Abraham Hang, MD; Megan M Hughes-Salabar, COA; Yin Allison Liu, MD, PhD
core  

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