Results 71 to 80 of about 3,058,814 (268)

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Fabrication and tolerance reduction of a Si-based pickup module for optical storage

open access: yes, 2011
We develop a miniaturized optical signal pickup module, with a working wavelength of 650 nm, and an image numerical aperture (NA) of 0.6, comprised of several SiNX optical phase elements on stacked Si substrates, for use in optical storage systems.
Lee, Chien-chien; Wang, Chin-ming; Huang, S.K.; Chang, J. Y.;Chi, Gou-chung; Hsu, S. C.; Liu, C. Y.
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Density of optical degrees of freedom : intensity, linear and angular momentum

open access: yes, 2014
For any optical system, optical eigenmodes describe solutions of Maxwells equations that are orthogonal to each other. In their simplest free space form, these modes correspond, for example, to Bessel, Laguerre-Gaussian or Hermite-Gaussian beams. However,
Michael Mazilu, Mazilu, Michael
core   +1 more source

High precision dynamic multi-interface profilometry with optical coherence tomography [PDF]

open access: yes, 2011
Optical coherence tomography (OCT) has mostly been used for high speed volume imaging but its profilometry potentials have not been fully exploited. This paper demonstrates high precision (as good as ~50nm) multi-interface profilometry using a Fourier ...
Lawman, S   +3 more
core   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Frequency stability of a self-phase-locked degenerate continuous-wave optical parametric oscillator [PDF]

open access: yes, 2003
The properties of a self-phase-locked by-2-divider optical parametric oscillator are presented. A locking range of up to 156 MHz is measured, and the divider's relative frequency stability is shown to be better than 6/spl times/10/sup -14/
Boller, Klaus J.   +4 more
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

High sensitivity optical coherence detector optimization

open access: yes, 2001
An optimal optical filtering scheme for an optical coherence detection system gives very high detection sensitivities (-30dB) for a partially coherent source.
Coutinho, R.C.   +7 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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