Results 81 to 90 of about 4,583,978 (297)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Recent Advances in Electrochemical and Optical Sensing of Dopamine
Sensors, 2020 Nowadays, several neurological disorders and neurocrine tumours are associated with dopamine (DA) concentrations in various biological fluids. Highly accurate and ultrasensitive detection of DA levels in different biological samples in real-time can ...
Faten Bashar Kamal Eddin, Yap Wing Fen
doaj +1 more source
Active Faraday optical frequency standards [PDF]
, 2014 We propose the mechanism of active Faraday optical clock, and experimentally demonstrate active Faraday optical frequency standards based on 852 nm narrow bandwidth Faraday atomic filter by the method of velocity-selective optical pumping of cesium vapor.
Chen, Jingbiao, Zhuang, Wei
core +1 more source
Applied Optics, 2019 Starting from a peculiar image observed below a bubble that is floating at a water–air interface, this paper analyzes several optical properties of these special types of refracting objects (termed bubble axicons). Using mainly geometrical optics, their relation to common axicons, the shadow-sausage effect, and elementary optical catastrophes (caustics)
openaire +3 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Embolism vulnerability analysis of petals and leaves in three species of shrub Rhododendron
Guangxi ZhiwuClimate change has been observed to increase the frequency and intensity of drought, which can adversely affect plant growth and development. Therefore, it is crucial to quantify plant xylem resistance to embolism, particularly in the context of global ...
XIA Ying +4 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source