Results 81 to 90 of about 825,011 (350)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Operating penalties in single-fiber operation 10-Gb/s, 1024-way split, 110-km long-reach optical access networks [PDF]

open access: yes, 2006
We report for the first time optical signal-to-noise penalties which lead to performance degradations in single-fiber long-reach optical access networks when compared to identical dual-fiber systems.
Shea, D.P., Mitchell, J.E.
core  

Fault Tolerant Spectral/Spatial Optical Code Division Multiple Access Passive Optical Network

open access: yesSensors
High-capacity communication networks are built to provide high throughput and low latency to accommodate the growing demand for bandwidth. However, the provision of these features is subject to a robust underlying network, which can provide high capacity
Rahat Ullah   +8 more
doaj   +1 more source

Wavelength Reuse for Short-Reach Optical Access Network Utilizing MDM

open access: yesIEEE Photonics Journal, 2017
Wavelength reuse has been proposed as an effective solution to realize colorless optical network units (ONUs) for next-generation passive optical network with simplified maintenance and reduced cost.
Yuanxiang Chen   +9 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Nonlinear optical thresholding in a 4-Channel OCDMA system via two-photon absorption [PDF]

open access: yes, 2009
We demonstrate the use of a Two-Photon Absorption based detector in an OCDMA system.
K. J. Dexter   +12 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Performance assessment of a fast optical add-drop multiplexer-based metro access network with edge computing [PDF]

open access: yes, 2019
\u3cp\u3eNext-generation metro access nodes with edge computing need to be redesigned to co-allocate advanced optical technologies, computing, and storage resources to support the upcoming multiple applications in 5G.
Yan, F Fulong   +8 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Peer-to-Peer Federated Learning on Software-Defined Optical Access Network

open access: yesIEEE Access
Recent advancements in AI have significantly propelled machine learning (ML) as a cornerstone of modern technological infrastructure, especially in enhancing machine-to-machine (M2M) communication.
Andrew Fernando Pakpahan, I-Shyan Hwang
doaj   +1 more source

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