Results 71 to 80 of about 825,011 (350)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Applications of perfect difference codes in fiber-optics and wireless optical code-division multiplexing/multiple-access systems [PDF]
, 2012 After establishing itself in the radio domain, Spread spectrum code-division multiplexing/multiple-access (CDMA) has seen a recent upsurge in optical domain as well.
Umrani, Fahim Aziz
core +1 more source
An all-optical carrier recovery scheme for access networks with simple ASK modulation [PDF]
, 2011 We theoretically investigate and experimentally demonstrate a scheme for all-optical carrier recovery in loopback access networks that avoids orthogonal or complex modulation formats for the downstream or upstream signals.
Maziotis, A +20 more
core +1 more source
IEEE Access, 2019 For the rapid increase in the number of optical line terminals (OLTs) and optical network units (ONUs) connected to the control center in the software defined optical access network (SDOAN) environment, the security problems caused by the communication ...
Yongli Tang +4 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Reconfigurable nodes for passive optical networks (PON) [PDF]
, 2009 Mestrado em Engenharia Electrónica e TelecomunicaçõesRecentemente , as redes ópticas de nova geração têm sido motivo de acesa discussão nos meios científicos.
Ferreira, Marco Paulo Flores
core +1 more source
Optical multiple access by receiver access control protocol for optical wireless networks [PDF]
2011 IEEE GLOBECOM Workshops (GC Wkshps), 2011 Optical wireless networks often require more than one transmitter to maintain consistent connection with a single receiver. Accordingly, an efficient control mechanism is required to address challenges associated with multiple access to the receiver. This paper proposes a receiver access control (RAC) mechanism for optical wireless mesh networks that ...
Falahpour, Maryam +3 more
openaire +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Benchmarking and viability assessment of optical packet switching for metro networks [PDF]
, 2004 Optical packet switching (OPS) has been proposed as a strong candidate for future metro networks. This paper assesses the viability of an OPS-based ring architecture as proposed within the research project DAVID (Data And Voice Integration on DWDM ...
Van Caenegem, R. +31 more
core +1 more source