Results 41 to 50 of about 2,226,540 (235)

Optical Nonreciprocity in Double Optomechanical Systems with Quadratic Coupling

open access: yesPhotonics, 2022
In this paper, the optical nonreciprocal phenomena in double optomechanical systems with quadratic coupling are studied. Our model belongs to an optomechanical system in which three coupling modes coexist, that is, the two cavity fields are coupled with ...
Xinyu Ji   +3 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

E-band telecom-compatible 40 dB gain high-power bismuth-doped fiber amplifier with record power conversion efficiency

open access: yesAPL Photonics
Multi-band transmission is one of the key practical solutions to cope with the continuously growing demand on the capacity of optical communication networks without changing the huge existing fiber base.
Aleksandr Donodin   +5 more
doaj   +1 more source

Low-Polarization, Broad-Spectrum Semiconductor Optical Amplifiers

open access: yesNanomaterials
Polarization-insensitive semiconductor optical amplifiers (SOAs) in all-optical networks can improve the signal-light quality and transmission rate. Herein, to reduce the gain sensitivity to polarization, a multi-quantum-well SOA in the 1550 nm band is ...
Meng Zhang   +13 more
doaj   +1 more source

Measurement and Analysis of Temperature-Dependent Optical Modal Gain in Single-Layer InAs/InP(100) Quantum-Dot Amplifiers in the 1.6- to 1.8-$\mu\hbox{m}$ Wavelength Range

open access: yesIEEE Photonics Journal, 2012
In this paper, measurements and analysis of the small-signal net modal gain of single-layer InAs/InP(100) quantum-dot (QD) optical amplifiers are presented. The amplifiers use only a single layer of InAs QDs on top of a thin InAs quantum well.
Y. Jiao   +5 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Optical Fiber Amplifiers: Optimization and PerformanceEvaluation

open access: yesDiyala Journal of Engineering Sciences, 2019
This work demonstrates the simulation of two different types of optical fiber amplifiers (OFA) utilizing OptiSystem–10, namely, 3 m length of erbium doped fiber amplifier (EDFA) and 7 km length of Raman fiber amplifier (RFA).
A. k. Abass   +4 more
doaj   +1 more source

Comparing different nonlinearities in readout systems for optical neuromorphic computing networks

open access: yesScientific Reports, 2021
Nonlinear activation is a crucial building block of most machine-learning systems. However, unlike in the digital electrical domain, applying a saturating nonlinear function in a neural network in the analog optical domain is not as easy, especially in ...
Chonghuai Ma   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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