Results 21 to 30 of about 10,684 (241)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
PhotonicsMulti-band optical communication presents a promising avenue for the significant enhancement of fiber-optic transmission capacity without incurring additional costs related to new cable deployment via the utilization of the bandwidth beyond the ...
Cheng Guo +6 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Доклады Белорусского государственного университета информатики и радиоэлектроники, 2021 Gigabit passive optical networks (GPON) are the most advanced technology. The data transfer rate is 2.5 Gbps for downstream and 1.25 Gbps for upstreams. But this network architecture has a limited physical network length of 20 km. This is due to the high
A. D. Tussupov +2 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
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IEEE Photonics Journal, 2013 We propose and demonstrate the concept of a novel 1 × N lossless adaptive optical power splitter (OPS) structure integrating a software-driven Opto-VLSI processor, optical amplifiers, and an array of 4-f imaging systems.
Haithem A. B. Mustafa +2 more
doaj +1 more source
Optical Amplifiers for Access and Passive Optical Networks: A Tutorial
Applied Sciences, 2020 For many years, passive optical networks (PONs) have received a considerable amount of attention regarding their potential for providing broadband connectivity, especially in remote areas, to enable better life conditions for all citizens. However, it is
Tomas Horvath +3 more
doaj +1 more source
Floquet-Mode Traveling-Wave Parametric Amplifiers
PRX Quantum, 2022 Simultaneous ideal quantum measurements of multiple single-photon-level signals would advance applications in quantum information processing, metrology, and astronomy but require the first amplifier to be simultaneously broadband, quantum limited, and ...
Kaidong Peng +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
IEEE Access, 2021 Semiconductor optical amplifiers (SOAs) offer direct electrical injection, power consumption, integration, and anti-radiation advantages over optical fiber amplifiers.
Xin Li +11 more
doaj +1 more source