Results 61 to 70 of about 493,288 (280)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Optically-triggered deterministic spiking regimes in nanostructure resonant tunnelling diode-photodetectors

Neuromorphic Computing and Engineering, 2023
This work reports a nanostructure resonant tunnelling diode-photodetector (RTD-PD) device and demonstrates its operation as a controllable, optically-triggered excitable spike generator.
Qusay Raghib Ali Al-Taai, Matěj Hejda, Weikang Zhang, Bruno Romeira, José M L Figueiredo, Edward Wasige, Antonio Hurtado   +6 more
doaj   +1 more source

Towards quantum computing with single atoms and optical cavities on atom chips

, 2006
We report on recent developments in the integration of optical microresonators into atom chips and describe some fabrication and implementation challenges.
A. Beige, Anderson MH, Barrett SD, Beige A, Bennett CH, Blinov BB, Cirac JI, Cook RJ, Dehmelt HG, Deutsch D, DiVincenzo DP, E. A. Hinds, Ekert AK, Eriksson S, Feynman RP, Folman R, Gollasch C, Grover LK, Guthöhrlein GR, Haase A, Hegerfeldt GC, Horak P, Häffner H, J. Metz, Jones MPA, Kielpinski D, Knill E, Kreuter A, Kuhn A, Kuhn A, Leibfried D, Lim YL, Lim YL, Long R, Louyer Y, M. Trupke, Marr C, Maunz P, Maunz P, McKeever J, Meter RV, Nußmann S, Nußmann S, Osnaghi S, Pachos J, Pellizzari T, Protsenko IE, Raussendorf R, Reichel J, Rekdal PK, Rosenblit M, Sauer JA, Sauer JA, Sinclair CDJ, Tregenna B, Treutlein P, Trupke M, Vahala KJ, Vandersypen LMK, Walther P, Ye J, Yi XX, Zheng S-B   +62 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Dual-Band High-Throughput and High-Contrast All-Optical Topology Logic Gates

Micromachines
Optical computing offers advantages such as high bandwidth and low loss, playing a crucial role in signal processing, communication, and sensing applications.
Jinying Zhang, Yulin Si, Yexiaotong Zhang, Bingnan Wang, Xinye Wang   +4 more
doaj   +1 more source

Time‐Lapse Image Classification Using a Diffractive Neural Network

Advanced Intelligent Systems, 2023
Diffractive deep neural networks (D2NNs), comprised of spatially engineered passive surfaces, collectively process optical input information at the speed of light propagation through a thin diffractive volume, without any external computing power ...
Md Sadman Sakib Rahman, Aydogan Ozcan
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Optical holonomic quantum computer [PDF]

Physical Review A, 2000
16 pages, 3 figures ...
Pachos, Jiannis, Chountasis, Spiros
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source