Results 61 to 70 of about 3,745,295 (251)
Optical Computing and Computational Complexity
, 2006 This work concerns the computational complexity of a model of computation that is inspired by optical computers. The model is called the continuous space machine and operates in discrete timesteps over a number of two-dimensional images of fixed size and arbitrary spatial resolution.
openaire +2 more sources
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Dual-Band High-Throughput and High-Contrast All-Optical Topology Logic Gates
MicromachinesOptical computing offers advantages such as high bandwidth and low loss, playing a crucial role in signal processing, communication, and sensing applications.
Jinying Zhang +4 more
doaj +1 more source
Neuromorphic Computing and Engineering, 2023 This work reports a nanostructure resonant tunnelling diode-photodetector (RTD-PD) device and demonstrates its operation as a controllable, optically-triggered excitable spike generator.
Qusay Raghib Ali Al-Taai +6 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Time‐Lapse Image Classification Using a Diffractive Neural Network
Advanced Intelligent Systems, 2023 Diffractive deep neural networks (D2NNs), comprised of spatially engineered passive surfaces, collectively process optical input information at the speed of light propagation through a thin diffractive volume, without any external computing power ...
Md Sadman Sakib Rahman, Aydogan Ozcan
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 2019 \u3cp\u3eNext-generation metro access nodes with edge computing need to be redesigned to co-allocate advanced optical technologies, computing, and storage resources to support the upcoming multiple applications in 5G.
Yan, F Fulong +8 more
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source