Results 71 to 80 of about 3,745,295 (251)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Wavelength-diversity transmission for fading mitigation in the atmospheric optical communication channel [PDF]

, 2006
Mitigation of index of refraction turbulence (IRT) effects is crucial in long-range atmospheric communication links. Diversity-transmission is one favorable way for fading compensation.
Perlot, Nicolas, Hennes Henniger, Giggenbach, Dirk, Nicolas Perlot, Brandon L. Wilkerson, Henniger, Hennes, Wilkerson, Brandon, Dirk Giggenbach   +7 more
core   +1 more source

Monolithically integrated asynchronous optical recurrent accelerator

eLight
Computing with light is widely recognized as a promising paradigm for overcoming the energy and latency limitations of electronic computing. However, the energy consumption and latency in current optical computing hardware predominantly arise in the ...
Bo Wu, Haojun Zhou, Junwei Cheng, Wenkai Zhang, Shiji Zhang, Chaoran Huang, Dongmei Huang, Hailong Zhou, Jianji Dong, Xinliang Zhang   +9 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Evaluation of the Scintillation Loss for Optical Communication Systems with Direct Detection [PDF]

, 2006
In optical communications through the atmosphere, the evaluation of a link feasibility often requires the quantification of the scintillation penalty in terms of power loss. To find how much additional optical power is needed to reach the bit-error-rate (
Perlot, Nicolas
core  

Multiple Wavelength Free-Space Laser Communications [PDF]

, 2003
Free-space optical communications systems in the atmosphere, based on intensity modulation and direct detection, are heavily affected by fading caused by turbulence cells of varying scale and motion.
Perlot, Nicolas, Hennes Henniger, Giggenbach, Dirk, Nicolas Perlot, Henniger, Hennes, Florian David, Robert Purvinskis, David, Florian, Dirk Giggenbach, Purvinskis, Robert   +9 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Diffractive optical computing in free space

Nature Communications
Structured optical materials create new computing paradigms using photons, with transformative impact on various fields, including machine learning, computer vision, imaging, telecommunications, and sensing.
Jingtian Hu, Deniz Mengu, Dimitrios C. Tzarouchis, Brian Edwards, Nader Engheta, Aydogan Ozcan   +5 more
doaj   +1 more source

Parallel and Sequential Optical Computing [PDF]

, 2008
We present a number of computational complexity results for an optical model of computation called the continuous space machine. We also describe an implementation for an optical computing algorithm that can be easily defined within the model. Our optical model is designed to model a wide class of optical computers, such as matrix vector multipliers ...
Damien Woods, Thomas J. Naughton
openaire   +3 more sources