Results 91 to 100 of about 1,179,244 (300)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Parametrical study of the influence of the climatic data and the construction properties on the efficiency of a collector/storage solar water heater

Revue des Énergies Renouvelables, 2008
A study was undertaken on the performance of an integrated collector-storage solar water heater consisting of a cylindrical water storage tank combined with a parabolic reflector, manufactured at the Laboratory of Energetic and thermal Processes (LEPT ...
A. Teyeb, L. Dehmani, C. Kerkeni, L. Kaabi   +3 more
doaj  

Linear-Optical Processing Cannot Increase Photon Efficiency [PDF]

Physical Review Letters, 2010
4 pages, 3 ...
Berry, D. W., Lvovsky, A. I.
openaire   +3 more sources

Efficient nitrogen-vacancy centers' fluorescence excitation and collection from micrometer-sized diamond by a tapered optical fiber

, 2018
Efficiently excite nitrogen-vacancy (NV) centers in diamond and collect their fluorescence significantly benefit the fiber-optic-based NV sensors.
Arumugam, Sri Ranjini, Balasubramanian, Gopalakrishnan, Chang, Huan-Cheng, Du, Guanxiang, Duan, Dewen, Kavatamane, Vinaya Kumar, Tzeng, Yan-Kai   +6 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

A one-dimensional ultracold medium of extreme optical depth

, 2013
We report on the preparation of a one-dimensional ultracold medium in a hollow-core photonic crystal fiber, reaching an effective optical depth of 1000(150).
Blatt, Frank, Halfmann, Thomas, Peters, Thorsten   +2 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The role of nonlinear optical absorption in narrow-band difference frequency terahertz-wave generation

, 2009
We present a general analysis of the influence of nonlinear optical absorption on terahertz generation via optical difference frequency generation, when reaching for the quantum conversion efficiency limit.
Bivona, Saverio, Busacca, Alessandro C., Cherchi, Matteo, Cino, Alfonso C., Oliveri, Roberto L.   +4 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source