Results 41 to 50 of about 2,620 (256)

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

Arthritis Care &Research, Accepted Article.
Objective VEXAS syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures. A VEXAS‐specific disease activity index (DAI) is an essential tool for reliably capturing changes in disease ...
Kevin Byram, Heřman Mann, Danielle Hammond, Onima Chowdhury, Sinisa Savic, Yohei Kirino, Carmelo Gurnari, Maël Heiblig, Thibault Comont, Arsène Mekinian, Mrinal M. Patnaik, Lachelle D. Weeks, Gary Ho, Adam Al‐Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin‐Lavialle, Peter C. Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Raman Garcha, David B. Beck, Matthew J. Koster   +25 more
wiley   +1 more source

Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal

Advanced Science, EarlyView.
We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao, Yi Hou, Jie Zhang, Bo Wang, Minghui Guo, Hua Qu, Wei Rao, Jing Liu   +7 more
wiley   +1 more source

A Search for Minute-timescale Flares from the Transient AT 2024wpp

The Astrophysical Journal
The AT 2018cow-like fast blue optical transient AT 2022tsd showed a large number of a few-minute-duration, high-luminosity (∼10 ^43 erg s ^−1 ) flares. We present an intensive search for such flares from another 18cow-like event, AT 2024wpp. We have used
Eran O. Ofek, Lior Ozer, Ruslan Konno, Nimrod Strasman, Ping Chen, Sagi Ben-Ami, David Polishook, Alexander Krassilchtchikov, Simone Garrappa, Erez A. Zimmermann, Enrico Segre, Asaf Horowicz, Avishay Gal-Yam, Yarin M. Shani, Stanislav Fainer, Michael Engel, Yahel Sofer-Rimalt, Anna Y. Q. Ho, Yossi Shvartzvald, Ofer Yaron, Kris Rybicki, Arie Blumenzweig, Sarah Spitzer, Ron Arad   +23 more
doaj   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

The Double Tidal Disruption Event AT 2022dbl Implies that at Least Some “Standard” Optical Tidal Disruption Events Are Partial Disruptions

The Astrophysical Journal Letters
Flares produced following the tidal disruption of stars by supermassive black holes can reveal the properties of the otherwise dormant majority of black holes and the physics of accretion.
Lydia Makrygianni, Iair Arcavi, Megan Newsome, Ananya Bandopadhyay, Eric R. Coughlin, Itai Linial, Brenna Mockler, Eliot Quataert, Chris Nixon, Benjamin Godson, Miika Pursiainen, Giorgos Leloudas, K. Decker French, Adi Zitrin, Sara Faris, Marco C. Lam, Assaf Horesh, Itai Sfaradi, Michael Fausnaugh, Ehud Nakar, Kendall Ackley, Moira Andrews, Panos Charalampopoulos, Benjamin D. R. Davies, Yael Dgany, Martin J. Dyer, Joseph Farah, Rob Fender, David A. Green, D. Andrew Howell, Thomas Killestein, Niilo Koivisto, Joseph Lyman, Curtis McCully, Morgan A. Mitchell, Estefania Padilla Gonzalez, Lauren Rhodes, Anwesha Sahu, Giacomo Terreran, Ben Warwick   +39 more
doaj   +1 more source

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

Advanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu, Simin Bi, Zhechen Liu, Xiaofeng Zhou, Hengwei Qin, Nicola Dalbeth, Minbiao Ji, Yinghui Hua   +7 more
wiley   +1 more source

Machine Learning‐Assisted Design and Performance Prediction of a Compact Dual‐Band Polarization‐Insensitive THz Metamaterial Absorber for Skin‐Cancer‐Related Refractive‐Index Sensing

Advanced Electronic Materials, EarlyView.
A compact QASRR‐based THz metamaterial absorber enables polarization‐insensitive dual‐band absorption and skin‐cancer‐related refractive‐index sensing through measurable resonance shifts. Field, surface‐current, and circuit analyses clarify the dual‐resonance mechanism, while StackNet‐assisted prediction accurately estimates the simulated absorption ...
Md. Murad Kabir Nipun, S. M. Rifatur Rana, Md. Golam Morshed, Imrose Jahan, F. A. Sabbir Ahamed, Md. Jahedul Islam   +5 more
wiley   +1 more source

Fine-Grained Monitoring of Gas Flaring in Persian Gulf Countries With Multispectral SDGSAT-1 Nighttime Imagery

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Gas flaring is a major source of greenhouse gas and a waste of nonrenewable resources. Remote sensing is suggested to be a capable proxy to provide independent, reliable, and regular observations on global gas flaring.
Zheng Zhang, Dongmei Yan, Huadong Guo, Zhitao Zhao, Jun Yan, Ping Tang   +5 more
doaj   +1 more source

Observations and modelling of a large optical flare on AT Microscopii [PDF]

Astronomy & Astrophysics, 2002
11 pages, 8 tables, accepted by A& ...
Garcia-Alvarez, D., Jevremovic, D., Doyle, J. G., Butler, C. J., Observatory, Armagh, Observatory, Astronomical   +5 more
openaire   +2 more sources

Formation of Light‐Emitting Defects in Ag‐Based Memristors

Advanced Electronic Materials, EarlyView.
How does a memristor begin to emit light‐before it even conducts? This work reveals that nanoscale silver clusters form, diffuse, and aggregate during activation, driving early photoluminescence ahead of current flow. Linking these precursor dynamics to later electroluminescence, it uncovers the origins of light emission and enables precise control of ...
Diana Singh, Maciej Ćwierzona, Régis Parvaud, Sebastian Maćkowski, Alexandre Bouhelier   +4 more
wiley   +1 more source