Results 71 to 80 of about 4,961 (263)

Navigating AI with pedagogical purpose: Toward an anatomy‐centered framework for AI‐enhanced learning

Anatomical Sciences Education, EarlyView.
Abstract Artificial Intelligence (AI) has emerged as a transformative force in medical education, enabling customized, feedback‐rich, and immersive learning experiences. Anatomy education, as a discipline that is simultaneously visual, spatial, and clinically foundational, occupies a distinctive position within this technological landscape.
Rachel Jayasekhar, Gok Kandasamy
wiley   +1 more source

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

British Journal of Clinical Pharmacology, EarlyView.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili, Maurizio Evangelista, Elena Lucarini, Elena G. Giugliano, Carla Ghelardini, Laura Micheli, Lorenzo Di Cesare Mannelli   +6 more
wiley   +1 more source

Transfersomes with core and surface‐loaded NF‐κB p65 siRNA for enhanced transdermal transfection and effective treatment of psoriasis

BMEMat, EarlyView.
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing, Yuhui Yang, Ziyi Zhao, Kai Lv, Yiran Shao, Zhi Zhang, Dong Ma   +6 more
wiley   +1 more source

Loss, persistence and reversal of phenotypic traits

Biological Reviews, EarlyView.
ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni, Giuseppe Fusco, Filippo Nicolini, Heather Bruce, Andrea Luchetti   +4 more
wiley   +1 more source

Hybrid Kerr-electro-optic frequency combs on thin-film lithium niobate

Light: Science & Applications
Optical frequency combs are indispensable links between the optical and microwave domains. Chip-scale integration promises compact, scalable, and power-efficient frequency comb sources, enabled by the resonantly-enhanced Kerr effect or the electro-optic ...
Yunxiang Song, Yaowen Hu, Marko Lončar, Kiyoul Yang   +3 more
doaj   +1 more source

Evidence for adaptive explanations of semelparity in animals

Biological Reviews, EarlyView.
ABSTRACT Semelparity, the reproductive strategy of reproducing once, is widespread but uncommon in animals. Classes of models to explain the evolution of semelparity are based either on age structure and mortality schedules – demographic models in which high post‐reproductive mortality risk favours high reproductive effort and semelparity results from ...
Diana O. Fisher, Roberto Salguero‐Gómez   +1 more
wiley   +1 more source

Frequency Comb-Based WDM Transmission Systems Enabling Joint Signal Processing

Applied Sciences, 2018
We review the use of optical frequency combs in wavelength-division multiplexed (WDM) fiber optic communication systems. In particular, we focus on the unique possibilities that are opened up by the stability of the comb-line spacing and the phase ...
Lars Lundberg, Magnus Karlsson, Abel Lorences-Riesgo, Mikael Mazur, Victor Torres-Company, Jochen Schröder, Peter A. Andrekson   +6 more
doaj   +1 more source

Modular One‐Pot Access to π‐Expanded Tetrakis(Phenothiazinyl)‐Silanes With Broadly Tunable Redox and Emission Properties

Chemistry – A European Journal, EarlyView.
A library of 21 tetrakis(phenothiazinyl)‐substituted silanes with broadly variable substituent decoration, which are fully reversible multistage redox systems with intense tunable emission from deep blue to yellow–green (441–533 nm), was rapidly synthesized by bromine–lithium exchange/borylation–Suzuki coupling of tetrakis(4‐bromophenyl)silane or by ...
Thomas P. M. Merke, Lysander Presser, Leonard Karl, Christian Ganter, Thomas J. J. Müller   +4 more
wiley   +1 more source

An ultra-stable high-power optical frequency comb

APL Photonics
Optical frequency combs are typically generated in the near-infrared wavelength range, where many mode-locked lasers operate. Nonlinear frequency conversion can then be used to extend optical frequency metrology to other spectral regions, such as the ...
Fabian Schmid, Jorge Moreno, Johannes Weitenberg, Peter Russbüldt, Theodor W. Hänsch, Thomas Udem, Akira Ozawa   +6 more
doaj   +1 more source

Endless frequency shifting of optical frequency comb lines

Optics Express, 2013
The functional principle of a novel technique for frequency shifting lines of an optical frequency comb is demonstrated. The underlying principle is to shift the carrier frequency by changing the carrier phase within the time span between subsequent pulses of a mode-locked laser used as comb generator.
Erik, Benkler, Felix, Rohde, Harald R, Telle   +2 more
openaire   +2 more sources