Results 81 to 90 of about 1,157,540 (291)

Aberrations in shift-invariant linear optical imaging systems using partially coherent fields

, 2015
Here the role and influence of aberrations in optical imaging systems employing partially coherent complex scalar fields is studied. Imaging systems require aberrations to yield contrast in the output image. For linear shift-invariant optical systems, we
Beltran, Mario A., Kitchen, Marcus J., Paganin, David M., Petersen, T.   +3 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Optical Images and Source Catalog of AKARI North Ecliptic Pole Wide Survey Field

, 2010
We present the source catalog and the properties of the $B-, R-$, and $I-$band images obtained to support the {\it AKARI} North Ecliptic Pole Wide (NEP-Wide) survey.
Arnouts, Barkhouse, Bell, Bertin, Bertin, Bohlin, Capak, Couch, Fadda, Gawiser, Giavalisco, Glikman, Hogg, Huang, Hunt, Hwang, Hyung Mok Lee, Im, Im, Im, Induk Lee, Jester, Jones, Kang, Ko, Kron, Le Floc'h, Le Floc'h, Lee, Lee, Lim, Madau, Mamon, Mansur Ibrahimov, Matsuhara, Metcalfe, Monet, Myung Gyoon Lee, Myungshin Im, Nakamura, Postman, Reddy, Richards, Schlegel, Scoville, Shim, Shim, Shim, Silva, Smail, Steidel, Stevenson, Vanden Berk, Wada, Yasuda, Yiseul Jeon   +55 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Optical Illusion Images Dataset

INSAM Journal of Contemporary Music, Art and Technology, 2019
Human vision is capable of performing many tasks not optimized for during its long evolution. Reading text and identifying artificial objects such as road signs are both tasks that mammalian brains never encountered in the wild but are very easy for us to perform.
Robert Max Williams, Roman V. Yampolskiy
openaire   +3 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

An ICCD camera-based time-domain ultrasound-switchable fluorescence imaging system

Scientific Reports, 2019
Fluorescence imaging in centimeter-deep tissues with high resolution is highly desirable for many biomedical applications. Recently, we have developed a new imaging modality, ultrasound-switchable fluorescence (USF) imaging, for achieving this goal.
Shuai Yu, Tingfeng Yao, Baohong Yuan
doaj   +1 more source

Sensitivity of synthetic aperture laser optical feedback imaging

, 2012
In this paper we compare the sensitivity of two imaging configurations both based on Laser Optical Feedback Imaging (LOFI). The first one is direct imaging, which uses conventional optical focalisation on target and the second one is made by Synthetic ...
Aleksoff, Bramati, Day, Dubois, Dubois, Eric Lacot, Hugon, Hugon, Hugon, Hugues Guillet de Chatellus, Jacquin, Jacquin, Jacquin, Kolobov, Lacot, Lacot, Lacot, Liu, Markus, Minsky, Muzet, Olivier Hugon, Olivier Jacquin, Otsuka, Otsuka, Pantazis, Pernot, Popoff, Sudo, Vellekoop, Vertu, Wilfried Glastre, Witomski, Witomski   +33 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source