Results 71 to 80 of about 661,323 (302)
Theoretical Model of Curved Liquid Surface in the Microholes for Molding Microlenses
OpticsMicrolenses are essential optics widely used in many fields. The microfluidics-assisted fabrication method provides a rapid, convenient way to manufacture microlenses. However, there is no mathematical model to describe the profile of the liquid surface.
Yuyang Shi +5 more
doaj +1 more source
A Precision Angle Sensor using an Optical Lever inside a Sagnac Interferometer
, 2011 We built an ultra low noise angle sensor by combining a folded optical lever and a Sagnac interferometer. The instrument has a measured noise floor of 1.3 prad / Hz^(1/2) at 2.4 kHz.
A. Sugarbaker +14 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
BiosensorsSurface plasmon resonance (SPR) biosensors have experienced rapid development in recent years and have been widely applied in various fields. Angular-interrogation SPR biosensors play an important role in the field of biological detection due to their ...
Xiantong Yu +6 more
doaj +1 more source
Long range laser traversing system [PDF]
, 1974 The relative azimuth bearing between first and second spaced terrestrial points which may be obscured from each other by intervening terrain is measured by placing at one of the points a laser source for projecting a collimated beam upwardly in the ...
Caudill, L. O.
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Comparison of laboratory calibrations of the Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) at the beginning and end of the first flight season [PDF]
Spectral and radiometric calibrations of the Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) were performed in the laboratory in June and November, 1987, at the beginning and end of the first flight season.
Chrien, Thomas G. +4 more
core +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Laser vibration analyzer [PDF]
, 1971 Instrument system uses laser and optical heterodyne receiver to measure Doppler phase shifts produced on a laser beam by the deflection of the vibrating surface of a structure under test or in ...
Foster, J. V.
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source