Results 91 to 100 of about 4,875,232 (303)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
IEEE Photonics Journal, 2017 A magnetic field sensor based on the magnetic-field-induced nanoparticle assembly effect in microcapillary whispering gallery mode (WGM) ring resonator is proposed and experimentally demonstrated.
Zhe Yu +6 more
doaj +1 more source
Plastinated tissue samples as three-dimensional models for optical instrument characterization
Optics Express, 2008 Histology of biological specimens is largely limited to investigating two-dimensional structure because of the sectioning required to produce optically thin samples for conventional microscopy.
D. Marks, E. Chaney, S. Boppart
semanticscholar +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
An autonomous intelligent mosquito sentinel for field-deployed surveillance
Communications EngineeringMosquito-borne diseases pose a major public health challenge and require effective, scalable surveillance to guide targeted interventions. Existing monitoring techniques, ranging from manual morphological identification to acoustic, optical, and ...
Nuofei Lin +7 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Design and testing of an optical instrument for skin flap monitoring. [PDF]
Sci Rep, 2023 Moreno-Oyervides A +6 more
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Design optimization of a flexure spring used in small-sized ultra-precise optical instrument. [PDF]
Heliyon, 2023 Kim J, Lee DC, Kim HS.
europepmc +1 more source