Results 91 to 100 of about 661,323 (302)

10 um wavefront spatial filtering: first results with chalcogenide fibers

, 2003
Wavefront cleaning by single-mode fibers has proved to be efficient in optical-infrared interferometry to improve calibration quality. For instance, the FLUOR instrument has demonstrated the capability of fluoride glass single-mode fibers in this respect
Amy-Klein, Anne, Borde, Pascal, Daussy, Christophe, Leger, Alain, Maze, Gwenael, Nguyen, Thanh, Perrin, Guy, Raynal, Pierre-Ivan   +7 more
core   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

A Novel Optical Instrument for Measuring Mass Concentration and Particle Size in Real Time. [PDF]

Sensors (Basel), 2023
Zhang J, Zhang Z, Hou L, Zhou W.
europepmc   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Design and Development of a Bimodal Optical Instrument for Simultaneous Vibrational Spectroscopy Measurements. [PDF]

Int J Mol Sci, 2022
Arévalo LA, O'Brien SA, Lopez E, Singh GP, Seifert A.   +4 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Halogen occultation experiment (HALOE) optical witness-plate program [PDF]

An optical witness plate program was implemented to monitor buildup of molecular contamination in the clean room during the assembly and testing of the Halogen Occulation Experiment (HALOE) instrument.
Harvey, Gale A., Raper, James L.
core   +1 more source

Precision mounting for instrument optical elements provided by polyimide bonding [PDF]

, 1969
Epoxy resin-coated polyimide plastic is used for bonding materials with different thermal coefficients in applications requiring precision mounting, especially where vibrations, temperature extremes, and low pressures are encountered.
Mueller, T. F.
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

All-Sky Near Infrared Space Astrometry [PDF]

, 2019
Gaia is currently revolutionizing modern astronomy. However, much of the Galactic plane, center and the spiral arm regions are obscured by interstellar extinction, rendering them inaccessible because Gaia is an optical instrument.
Bartlett, Jennifer Lynn, Bendek, Eduardo, Benedict, Fritz, Boehm, Celine, Brown, Anthony, Conroy, Charlie, Fynbo, Johan Peter Uldall, Gnedin, Oleg, Hillenbrand, Lynne, Hobbs, David, Høg, Erik, Lindegren, Lennart, Makarov, Valeri, Martins, Alberto Krone, McArthur, Barbara, Rodriguez, David R., Shao, Mike, Sozzetti, Alessandro, Tomsick, John, Turyshev, Slava, Unwin, Stephen, White, Rick, Zhai, ChengXing   +22 more
core   +2 more sources