Results 51 to 60 of about 466,055 (265)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Optical investigations on oxycelluloses

open access: yesDie Makromolekulare Chemie, 1951
AbstractEs wird versucht, den Verlauf des oxydativen Celluloseabbaues durch verschiedene Oxydationsmittel (Periodat, Bichromat, Hypobromit) mit Hilfe von optischen Methoden zu differenzieren. Als Versuchsmaterial wird gebleichte Ramie der Firma Ernst H. Fischer's Söhne A. G.
openaire   +3 more sources

On the Fiber Geometry Dependence of Forward Stimulated Brillouin Scattering in Optical Fiber

open access: yesAdvanced Photonics Research, 2023
Nowadays, forward Brillouin scattering in optical fibers has attracted massive research interests worldwide, owing to its great potential for applications in sensing, filtering, lasing, and all‐optical signal processing, etc. The manipulation of spectrum
Yunshan Zhou   +3 more
doaj   +1 more source

Energetical and Exergetical Analyses of a Concentrating PV/T Collector: A Numerical Approach

open access: yesApplied Sciences, 2023
The specific work presents an optical and thermal investigation of a hybrid thermo-photovoltaic solar collector with an asymmetrical compound parabolic mirror.
Theodoros Papingiotis   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Optical Diagnostics during Pulsed Laser Ablation in Liquid (PLAL) for the Production of Metallic Nanoparticles

open access: yesApplied Sciences, 2021
Pulsed laser ablation in liquid (PLAL) is gaining an important role as a methodology for producing nanostructures without the use of chemicals and stabilizers.
Marcella Dell’Aglio   +1 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Observing single cells in whole organs with optical imaging

open access: yesJournal of Innovative Optical Health Sciences, 2023
Cells are the basic unit of human organs that are not fully understood. The revolutionary advancements of optical imaging allowed us to observe single cells in whole organs, revealing the complicated composition of cells with spatial information ...
Xiaoquan Yang   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Pengaruh Pembelajaran Group Investigation dengan Multi Representasi pada Topik Alat-Alat Optik terhadap Penalaran Ilmiah dan Kemampuan Masalah Siswa SMA

open access: yesJurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2020
: The purpose of this study is to determine the impact of group investigation learning model with multi representation on the topic of optical devices on scientific reasoning and problem solving skill. This study were carried out using quasi experimental
Apolonia Delviyanti Putri Marga   +2 more
doaj   +1 more source

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