Results 71 to 80 of about 5,943,244 (298)

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

En face OCT

open access: yesVision Pan-America, 2014
Optical coherence tomography (OCT) is a noninvasive high resolution optical imaging technology based on interference between signal from an object under investigation and a local reference signal.
Andre Romano, Bruno Lumbroso
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Distortion and noise problems of subcarrier multiplexed optical systems

open access: yesJournal of Telecommunications and Information Technology, 2001
In this paper investigation of subcarrier multiplexed optical subsystems for optically supported communication systems is presented. Noise and spurious free dynamic range are the main parameters, which are determined by the applied optical transmission.
Eszter Udvary, Tam´as Marozsak
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Optical Investigation of Eu3+ Doped Bi12GeO20 (BGO) Crystals

open access: yesCrystals, 2020
The spectroscopic properties of Eu3+ doped Bi12GeO20 (BGO) sillenite bulk crystals that were grown by the low-thermal-gradient Czochralski technique (LTG Cz) were investigated. The absorption spectra and the emission properties have been measured at room
M. Kowalczyk   +6 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

ELECTROPHYSIOLOGICAL INVESTIGATIONS ON THE PIGEON'S OPTIC TECTUM [PDF]

open access: yesQuarterly Journal of Experimental Physiology and Cognate Medical Sciences, 1971
Electrical responses of the cells at different depths of the pigeon's optic tectum to different visual stimuli were recorded.Point to point representation of the upper visual field on the dorsal surface of the tectum was obtained as a projection on a horizontal stereotaxic plane.Different units in the stratum griseum et fibrosum superficiale of the ...
openaire   +2 more sources

An Error Protection Protocol for user-transparent bridging of Fast Ethernet data transmission over the optical fading channel in an Aeronautical environment [PDF]

open access: yes, 2008
This paper presents an extensive insight into error protection techniques for free space optical links, focusing in particular in aeronautic stratospherically applications.
Serrano-Solsona, Clara   +2 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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