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Optical manipulation for single‐cell studies
Journal of Biophotonics, 2010AbstractIn the last decade optical manipulation has evolved from a field of interest for physicists to a versatile tool widely used within life sciences. This has been made possible in particular due to the development of a large variety of imaging techniques that allow detailed information to be gained from investigations of single cells.
Kerstin, Ramser, Dag, Hanstorp
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Imaging and Optically Manipulating Neuronal Ensembles
Annual Review of Biophysics, 2017The neural code that relates the firing of neurons to the generation of behavior and mental states must be implemented by spatiotemporal patterns of activity across neuronal populations. These patterns engage selective groups of neurons, called neuronal ensembles, which are emergent building blocks of neural circuits.
Luis, Carrillo-Reid +4 more
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4D optical multibeam manipulation
SPIE Proceedings, 2005The Generalized Phase Contrast (GPC) method enables virtually loss free conversion of spatial phase patterns to highly efficient light intensity distributions. The GPC-method has been used in a number of applications requiring parallel light-beam encoding such as in advanced user-controlled optical micro-manipulation, wavefront sensing and generation ...
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Optical manipulation using optimal annular vortices
Optics Letters, 2016We discuss a simple method to generate a configurable annular vortex beam (AVB) with the maximum possible peak intensity, employing a phase hologram whose transmittance is the phase of a Bessel beam. Due to its maximum intensity, the AVB provides the optimal density of the orbital angular moment. Another attribute of the generated AVB is the relatively
Rafael, Paez-Lopez +3 more
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Optical Trapping and Manipulation Using Optical Fibers
Advanced Fiber Materials, 2019An optical trap forms a restoring optical force field to immobilize and manipulate tiny objects. A fiber optical trap is capable of establishing the restoring optical force field using one or a few pieces of optical fiber, and it greatly simplifies the optical setup by removing bulky optical components, such as microscope objectives from the working ...
Yuanhao Lou, Dan Wu, Yuanjie Pang
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2016
Single-cell analysis can reveal cell behaviors that are unobservable by traditional bulk measurements. The analysis of single cells is made possible by technology that enables the addressing and manipulation of microscale objects. Optical manipulators are capable of micro- and nano-manipulation and are attractive for single-cell procedures, due to ...
Julian Cheng +2 more
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Single-cell analysis can reveal cell behaviors that are unobservable by traditional bulk measurements. The analysis of single cells is made possible by technology that enables the addressing and manipulation of microscale objects. Optical manipulators are capable of micro- and nano-manipulation and are attractive for single-cell procedures, due to ...
Julian Cheng +2 more
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Optical vortices: Optical manipulation to crystal dislocations
Physica C: Superconductivity and its Applications, 2008Optical vortices are an interesting phenomenon, showing analogous behaviour to other vortices and screw dislocations found in physics and having many applications. We review here some of our work on optical vortices; covering their production, their use in manipulating low-refractive index micro-particles, the effects seen because of the orbital ...
MacDonald, Michael P., Dholakia, Kishan
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Parallel Optical Manipulation in Evanescent Optical Landscapes
Frontiers in Optics 2008/Laser Science XXIV/Plasmonics and Metamaterials/Optical Fabrication and Testing, 2008Using multiple-beam interference and total internal reflection, we couple an evanescent optical field to a large number of particles in a periodical landscape. The particles are confined and manipulated modifying the parameters of the landscape.
Carlos López-Mariscal, Kris Helmerson
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Optical Manipulation in Aerosol Optical Tweezers
2011Condensed phase optical manipulation techniques were pioneered by Ashkin, who demonstrated the first use of radiation pressure to guide particles in 1970 and later the first single-beam gradient force trap (optical tweezers) in 1986. Since then there have been numerous studies that make use of condensed phase optical tweezers, and that have sought to ...
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
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