Results 111 to 120 of about 3,449,089 (306)

Singapore 1:25,000 road map [cartographic material] /

open access: yes, 2010
Planimetric map of Singapore showing selected buildings, points of interest, and schools.; Some sheets include insets.; Includes list of schools.
Singapore. Ministry of Defence. Mapping Unit.
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Map of Norfolk Island [cartographic material] : Drawn and reproduced by the National Mapping Office, Dept. of the Interior.

open access: yes, 1956
Relief shown by spot heights and contours. Contour at 100 ft.; "NMO/56/50"; Also available online http://nla.gov.au/nla.map-vn1758341.
Australia. National Mapping Office.
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Antarctica compared with Australia and the British Isles [cartographic material]

open access: yes, 1969
Comparative area map of Antarctica, Australia and the British Isles, with images to scale of the British Isles imposed over Australia which is in turn imposed over Antarctica.; Also available online http://nla.gov.au/nla.map-vn4649833; National Library's
Australia. Division of National Mapping.
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Tasmania 1:25 000 series [cartographic material] /

open access: yes, 1979
Topographic map series with cadastral information. Relief shown by contours and spot heights. Depths shown by soundings.; "Tasmap."; Sheets of various eds.; Some sheets are issued by: Mapping Division, Department of Lands, Parks and Wildlife; Mapping ...
Tasmania. Lands Department Mapping Division.
core  

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