Results 91 to 100 of about 581,508 (291)

Synapse-specific inhibitory control of hippocampal feedback inhibitory circuit

Frontiers in Cellular Neuroscience, 2010
Local circuit and long-range GABAergic projections provide powerful inhibitory control over the operation of hippocampal inhibitory circuits, yet little is known about the input- and target-specific organization of interacting inhibitory networks in ...
Simon eChamberland, Simon eChamberland, Charleen eSalesse, Charleen eSalesse, Dimitry eTopolnik, Lisa eTopolnik, Lisa eTopolnik   +6 more
doaj   +1 more source

Dynamical response of ultracold interacting fermion-boson mixtures

, 2014
We analyze the dynamical response of a ultracold binary gas mixture in presence of strong boson-fermion couplings. Mapping the problem onto that of the optical response of a metal/semiconductor electronic degrees of freedom to electromagnetic ...
Ji, Kai, Komnik, Andreas, Maier, Stefan
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Optical mapping in plant comparative genomics [PDF]

GigaScience, 2015
Optical mapping has been widely used to improve de novo plant genome assemblies, including rice, maize, Medicago, Amborella, tomato and wheat, with more genomes in the pipeline. Optical mapping provides long-range information of the genome and can more easily identify large structural variations.
Tang, Haibao, Lyons, Eric, Town, Christopher D   +2 more
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Optical Calibration of a Multi-Color Ellipsometric Mapping Tool Fabricated Using Cheap Parts

Photonics
We developed and applied a new calibration method to make more accurate measurements with our multi-color ellipsometric mapping tool made from cheap parts.
Berhane Nugusse Zereay, Sándor Kálvin, György Juhász, Csaba Major, Péter Petrik, Zoltán György Horváth, Miklós Fried   +6 more
doaj   +1 more source

A Tentative Size-Luminosity Relation for the Iron Emission-Line Region in Quasars

, 2014
New reverberation mapping measurements of the size of the optical iron emission-line region in quasars are provided, and a tentative size-luminosity relation for this component is reported.
Barth, Aaron J., Chelouche, Doron, Cotlier, Gabriel I., Kaspi, Shai, Rafter, Stephen E.   +4 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Myofibroblasts impair myocardial impulse propagation by heterocellular connexin43 gap-junctional coupling through micropores

Frontiers in Physiology
Aim: Composite population of myofibroblasts (MFs) within myocardial tissue is known to alter impulse propagation, leading to arrhythmias. However, it remains unclear whether and how MFs alter their propagation patterns when contacting cardiomyocytes (CMs)
Yumika Tsuji, Yumika Tsuji, Takehiro Ogata, Kentaro Mochizuki, Shoko Tamura, Yuma Morishita, Tetsuro Takamatsu, Tetsuro Takamatsu, Satoaki Matoba, Hideo Tanaka, Hideo Tanaka   +10 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source