Results 71 to 80 of about 581,508 (291)

Optical Electrophysiology in the Developing Heart

Journal of Cardiovascular Development and Disease, 2018
The heart is the first organ system to form in the embryo. Over the course of development, cardiomyocytes with differing morphogenetic, molecular, and physiological characteristics are specified and differentiate and integrate with one another to ...
Kandace Thomas, Julie Goudy, Trevor Henley, Michael Bressan   +3 more
doaj   +1 more source

Neonatal Deletion of Hand1 and Hand2 within Murine Cardiac Conduction System Reveals a Novel Role for HAND2 in Rhythm Homeostasis

Journal of Cardiovascular Development and Disease, 2022
The cardiac conduction system, a network of specialized cells, is required for the functioning of the heart. The basic helix loop helix factors Hand1 and Hand2 are required for cardiac morphogenesis and have been implicated in cardiac conduction system ...
Rajani M. George, Shuai Guo, Beth A. Firulli, Michael Rubart, Anthony B. Firulli   +4 more
doaj   +1 more source

Comprehensive experimental analysis of nonlinear dynamics in an optically-injected semiconductor laser [PDF]

, 2011
We present the first comprehensive experimental study, to our knowledge, of the routes between nonlinear dynamics induced in a semiconductor laser under external optical injection based on an analysis of time-averaged measurements of the optical and RF ...
Adams, Michael J, Henning, Ian D, Hurtado, Antonio, Schires, Kevin   +3 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Marker-Free Tracking for Motion Artifact Compensation and Deformation Measurements in Optical Mapping Videos of Contracting Hearts

Frontiers in Physiology, 2018
Optical mapping is a high-resolution fluorescence imaging technique, which provides highly detailed visualizations of the electrophysiological wave phenomena, which trigger the beating of the heart.
Jan Christoph, Jan Christoph, Jan Christoph, Stefan Luther, Stefan Luther, Stefan Luther, Stefan Luther   +6 more
doaj   +1 more source

Importance of far-infrared mapping in a spiral galaxy: AKARI observation of M81

, 2010
The importance of the far-infrared (FIR) mapping is demonstrated for a face-on spiral galaxy, M81, by analyzing its imaging data at 65, 90, and 140 {\mu}m taken by AKARI.
Aannestad, Ai-Lei Sun, Baggett, Bendo, Braun, Buat, Cheng, Dale, Dale, Draine, Draine, Draine, Freedman, Harper, Hibi, Hirashita, Hirashita, Hirashita, Hiroyuki Hirashita, Inoue, Kawada, Kennicutt, Li, Lowe, Mathis, Mathis, Murakami, Nagata, Pilbratt, Poglitsch, Pollo, Pérez-González, Reach, Rice, Rots, Sauvage, Shibai, Shirahata, Suzuki, Suzuki, Takeuchi, Walterbos, Weingartner, Yamamura   +43 more
core   +1 more source

Optical mapping of neuronal activity during seizures in zebrafish [PDF]

, 2017
Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a better understanding of the mechanisms underlying this pathology and improve our approaches to the development of new drugs.
Fornetto, C, M\ufcllenbroich, M. C, Mannaioni, G, Marchetto, Giulia, Masi, A, Pavone, F. S, Resta, F, Tiso, Natascia, Turrini, L, Vanzi, F., Vettori, Andrea   +10 more
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Simultaneous Quantification of Spatially Discordant Alternans in Voltage and Intracellular Calcium in Langendorff-Perfused Rabbit Hearts and Inconsistencies with Models of Cardiac Action Potentials and Ca Transients

Frontiers in Physiology, 2017
Rationale: Discordant alternans, a phenomenon in which the action potential duration (APDs) and/or intracellular calcium transient durations (CaDs) in different spatial regions of cardiac tissue are out of phase, present a dynamical instability for ...
Ilija Uzelac, Yanyan C. Ji, Daniel Hornung, Johannes Schröder-Scheteling, Stefan Luther, Richard A. Gray, Elizabeth M. Cherry, Flavio H. Fenton   +7 more
doaj   +1 more source

Arrhythmic Risk Assessment of Hypokalaemia Using Human Pluripotent Stem Cell-Derived Cardiac Anisotropic Sheets

Frontiers in Cell and Developmental Biology, 2021
Introduction: Hypokalaemia, defined as an extracellular concentration of K+ below 3.5 mM, can cause cardiac arrhythmias by triggered or re-entrant mechanisms.
Bimal Gurung, Gary Tse, Gary Tse, Gary Tse, Wendy Keung, Wendy Keung, Ronald A. Li, Wing Tak Wong, Wing Tak Wong, Wing Tak Wong   +9 more
doaj   +1 more source