Results 51 to 60 of about 581,508 (291)

Optical Mapping Approaches on Muscleblind‐Like Compound Knockout Mice for Understanding Mechanistic Insights Into Ventricular Arrhythmias in Myotonic Dystrophy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundCardiac arrhythmias are common causes of death in patients with myotonic dystrophy (dystrophia myotonica [DM]). Evidence shows that atrial tachyarrhythmia is an independent risk factor for sudden death; however, the relationship is unclear ...
Chung‐Chuan Chou, Po‐Cheng Chang, Yi‐Chia Wei, Kuang‐Yung Lee   +3 more
doaj   +1 more source

Optical conductivity of one-dimensional doped Hubbard-Mott insulator

, 2002
We study the optical response of a strongly correlated electron system near the metal-insulator transition using a mapping to the sine-Gordon model. With semiclassical quantization, the spectral weight is distributed between a Drude peak and absorption ...
A. Luther, D. Controzzi, D. N. Aristov, D.N. Aristov, E. Jeckelmann, E. Papa, F. Gebhard, F.B. Gallagher, F.H.L. Essler, J. Voit, J.-S. Caux, J.M.P. Carmelo, M. Dumm, M. Fleck, M. Mori, P. Sengupta, R.F. Dashen, T. Giamarchi, T. Giamarchi, T. Kawamoto, T. Osafune, V.G. Emery, Vadim V. Cheianov, W. Barford, W. Henderson, W. Stephan, Y. Taguchi   +26 more
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Optical Imaging of Ventricular Action Potentials in a Torso Tank: A New Platform for Non-Invasive Electrocardiographic Imaging Validation

Frontiers in Physiology, 2019
Background: Non-invasive electrocardiographic imaging (ECGI) is a promising tool to provide high-resolution panoramic imaging of cardiac electrical activity noninvasively from body surface potential measurements.
Laura R. Bear, Laura R. Bear, Laura R. Bear, Richard D. Walton, Richard D. Walton, Richard D. Walton, Emma Abell, Emma Abell, Emma Abell, Yves Coudière, Yves Coudière, Yves Coudière, Yves Coudière, Michel Haissaguerre, Michel Haissaguerre, Michel Haissaguerre, Michel Haissaguerre, Olivier Bernus, Olivier Bernus, Olivier Bernus, Rémi Dubois, Rémi Dubois, Rémi Dubois   +22 more
doaj   +1 more source

Circle Method for Robust Estimation of Local Conduction Velocity High-Density Maps From Optical Mapping Data: Characterization of Radiofrequency Ablation Sites

Frontiers in Physiology, 2022
Conduction velocity (CV) slowing is associated with atrial fibrillation (AF) and reentrant ventricular tachycardia (VT). Clinical electroanatomical mapping systems used to localize AF or VT sources as ablation targets remain limited by the number of ...
Jimena G. Siles-Paredes, Jimena G. Siles-Paredes, Christopher J. Crowley, Flavio H. Fenton, Neal Bhatia, Shahriar Iravanian, Italo Sandoval, Stefan Pollnow, Olaf Dössel, João Salinet, João Salinet, Ilija Uzelac   +11 more
doaj   +1 more source

High-density diffuse optical tomography for imaging human brain function [PDF]

, 2019
This review describes the unique opportunities and challenges for noninvasive optical mapping of human brain function. Diffuse optical methods offer safe, portable, and radiation free alternatives to traditional technologies like positron emission ...
Culver, Joseph P, Eggebrecht, Adam T, Wheelock, Muriah D   +2 more
core   +1 more source

Statistical Significance of Optical Map Alignments [PDF]

Journal of Computational Biology, 2012
Abstract The Optical Mapping System constructs ordered restriction maps spanning entire genomes through the assembly and analysis of large datasets comprising individually analyzed genomic DNA molecules. Such restriction maps uniquely reveal mammalian genome structure and variation, but also raise computational and statistical ...
Deepayan Sarkar, Steve Goldstein, David C. Schwartz, Michael A. Newton   +3 more
openaire   +2 more sources

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Multi-Scale Assessments of Cardiac Electrophysiology Reveal Regional Heterogeneity in Health and Disease

Journal of Cardiovascular Development and Disease, 2018
The left and right ventricles of the four-chambered heart have distinct developmental origins and functions. Chamber-specific developmental programming underlies the differential gene expression of ion channel subunits regulating cardiac ...
Catherine E. Lipovsky, Brittany D. Brumback, Aditi Khandekar, Stacey L. Rentschler   +3 more
doaj   +1 more source

Cardiac Optical Mapping in Situ in Swine Models: A View of the Current Situation

Medicina, 2020
Optical mapping is recognized as a promising tool for the registration of electrical activity in the heart. Most cardiac optical mapping experiments are performed in ex vivo isolated heart models. However, the electrophysiological properties of the heart
Irma Martišienė, Regina Mačianskienė, Rimantas Benetis, Jonas Jurevičius   +3 more
doaj   +1 more source