Results 51 to 60 of about 3,449,089 (306)

Circle Method for Robust Estimation of Local Conduction Velocity High-Density Maps From Optical Mapping Data: Characterization of Radiofrequency Ablation Sites

open access: yesFrontiers in Physiology, 2022
Conduction velocity (CV) slowing is associated with atrial fibrillation (AF) and reentrant ventricular tachycardia (VT). Clinical electroanatomical mapping systems used to localize AF or VT sources as ablation targets remain limited by the number of ...
Jimena G. Siles-Paredes   +11 more
doaj   +1 more source

Proof of principle for shotgun DNA mapping by unzipping [PDF]

open access: yes, 2009
Ability to map polymerases and nucleosomes on chromatin is important for understanding the impact of chromatin remodeling on key cellular processes. Current methods (such as ChIP and ChIP-chip) have produced a wealth of information that demonstrates ...
Steven J. Koch   +12 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Capturing structure and function in an embryonic heart with Biophotonic tools

open access: yesFrontiers in Physiology, 2014
Disturbed cardiac function (flow, excitation, contraction, calcium transients) at an early stage of development has been shown to correlate with and may lead to cellular/molecular, functional and structural cardiac anomalies at later stages culminating ...
Ganga eKarunamuni   +9 more
doaj   +1 more source

Antiarrhythmic Properties of Elsholtzia ciliata Essential Oil on Electrical Activity of the Isolated Rabbit Heart and Preferential Inhibition of Sodium Conductance

open access: yesBiomolecules, 2020
Elsholtzia ciliata essential oil (E. ciliata) has been developed in Lithuania and internationally patented as exerting antiarrhythmic properties. Here we demonstrate the pharmacological effects of this herbal preparation on cardiac electrical activity ...
Regina Mačianskienė   +7 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Optical Electrophysiology in the Developing Heart

open access: yesJournal of Cardiovascular Development and Disease, 2018
The heart is the first organ system to form in the embryo. Over the course of development, cardiomyocytes with differing morphogenetic, molecular, and physiological characteristics are specified and differentiate and integrate with one another to ...
Kandace Thomas   +3 more
doaj   +1 more source

Performance optimization of free-space optical communication protocols based on results from FSO demonstrations [PDF]

open access: yes, 2007
The mobile free-space optical channel mainly suffers from relatively long link outages, produced by short-term blockings of the line-of-sight (obstacles, clouds), pointing- and tracking-errors or deep signal-fades caused by index of refraction turbulence
Bernhard Epple, Epple, Bernhard
core   +1 more source

EP-PINNs: Cardiac Electrophysiology Characterisation Using Physics-Informed Neural Networks

open access: yesFrontiers in Cardiovascular Medicine, 2022
Accurately inferring underlying electrophysiological (EP) tissue properties from action potential recordings is expected to be clinically useful in the diagnosis and treatment of arrhythmias such as atrial fibrillation.
Clara Herrero Martin   +7 more
doaj   +1 more source

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