ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source
Chiral spin constrained assemblies for polarized optical mapping. [PDF]
Zhang M +14 more
europepmc +1 more source
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Quadruple parametric optical mapping to measure cardiac metabolism-excitation-contraction coupling. [PDF]
Mills A, George SA.
europepmc +1 more source
Far-Field and Non-Intrusive Optical Mapping of Nanoscale Structures. [PDF]
Guan G +6 more
europepmc +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
From Pig to Human: Endo-Epicardial Substrate Characterization Using Dual Optical Mapping. [PDF]
Siles J +5 more
europepmc +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Optical mapping of the interface between iPSC-derived grafts and swine myocardium suggests potential arrhythmia mechanisms. [PDF]
Guragain B +6 more
europepmc +1 more source
High-throughput longitudinal electrophysiology screening of mature chamber-specific hiPSC-CMs using optical mapping. [PDF]
Allan A +14 more
europepmc +1 more source

