Results 171 to 180 of about 581,508 (291)

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Protocol for dual-optical mapping of voltage and calcium sensors in human pluripotent stem cell-derived cardiomyocytes. [PDF]

STAR Protoc
Alibhai FJ, Masoumi A, Kim HJ, Kim N, Kim W, Gomez-Garcia J, Lee P, Laflamme MA.   +7 more
europepmc   +1 more source

An improved assembly of the pearl millet reference genome using Oxford Nanopore long reads and optical mapping. [PDF]

G3 (Bethesda), 2023
Salson M, Orjuela J, Mariac C, Zekraouï L, Couderc M, Arribat S, Rodde N, Faye A, Kane NA, Tranchant-Dubreuil C, Vigouroux Y, Berthouly-Salazar C.   +11 more
europepmc   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

High level of complexity and global diversity of the 3q29 locus revealed by optical mapping and long-read sequencing. [PDF]

Genome Med, 2023
Yilmaz F, Gurusamy U, Mosley TJ, Hallast P, Kim K, Mostovoy Y, Purcell RH, Shaikh TH, Zwick ME, Kwok PY, Lee C, Mulle JG.   +11 more
europepmc   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Protocol for high-resolution optical mapping of ex vivo rat heart for electrophysiological studies. [PDF]

STAR Protoc
Sung YL, Tsai YS, Chang CL, Hu YF.
europepmc   +1 more source

Upward propagation of gigantic jets revealed by 3D radio and optical mapping. [PDF]

Sci Adv, 2022
Boggs LD, Mach D, Bruning E, Liu N, van der Velde OA, Montanyá J, Cummer S, Palivec K, Chmielewski V, MacGorman D, Peterson M.   +10 more
europepmc   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Correction: Inhibition of EPAC1 signaling pathway alters atrial electrophysiology and prevents atrial fibrillation

Frontiers in Physiology
Bastien Guillot, Bastien Guillot, Arthur Boileve, Arthur Boileve, Richard Walton, Richard Walton, Alexandre Harfoush, Alexandre Harfoush, Caroline Conte, Caroline Conte, Yannis Sainte-Marie, Yannis Sainte-Marie, Sabine Charron, Sabine Charron, Olivier Bernus, Olivier Bernus, Alice Recalde, Alice Recalde, Laurent Sallé, Laurent Sallé, Fabien Brette, Fabien Brette, Fabien Brette, Frank Lezoualc’h, Frank Lezoualc’h   +24 more
doaj   +1 more source