Results 71 to 80 of about 24,735 (218)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Elastic and inelastic scattering of 15n ions by 11B at 84 MeV [PDF]

Ядерна фізика та енергетика, 2014
Angular distributions of the 11B + 15N elastic and inelastic scattering were measured at Elab (15N) = 84 MeV. The data were analyzed within the optical model and coupled-reaction-channels method.
A. T. Rudchik, O. V. Herashchenko, K. A. Chercas, A. A. Rudchik, S. Kliczewski, Val. M. Pirnak, E. Piasecki, K. Rusek, A. Trczińska, S. B. Sakuta, R. Siudak, I. Strojek, A. Stolarz, E. I. Koshchy, A. O. Barabash, A. P. Ilyin, O. A. Ponkratenko, Yu. M. Stepanenko, V. V. Uleshchenko, Yu. O. Shyrma, J. Choiński, A. Szczurek   +21 more
doaj  

Any-Optical-Model: A Universal Foundation Model for Optical Remote Sensing

Proceedings of the AAAI Conference on Artificial Intelligence
Optical satellites, with their diverse band layouts and ground sampling distances, supply indispensable evidence for tasks ranging from ecosystem surveillance to emergency response. However, significant discrepancies in band composition and spatial resolution across different optical sensors present major challenges for existing Remote Sensing ...
Xuyang Li, Chenyu Li 0002, Danfeng Hong
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Elastic and inelastic scattering of 14N ions by 7Li at 80 MeV [PDF]

Ядерна фізика та енергетика, 2012
Angular distributions of the 7Li + 14N elastic and inelastic scattering as well as the 7Li(14N, Х) reactions with production of 13, 15, 16N + 8, 6, 5Li, 11, 12, 13, 14С + 10, 9, 8, 7Ве, 10, 11, 12В + 11, 10, 9В nuclei and others were measured at Elab ...
A. T. Rudchik, O. V. Gerashchenko, A. A. Rudchik, E. I. Koshchy, S. Kliczewski, K. Rusek, S. Yu. Mezhevych, V. A. Plujko, O. A. Ponkratenko, Val. M. Pirnak, A. P. Ilyin, V. V. Uleshchenko, R. Siudak, J. Choiński, B. Czech, A. Szczurek   +15 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Bumblebee visual allometry results in locally improved resolution and globally improved sensitivity

eLife, 2019
The quality of visual information that is available to an animal is limited by the size of its eyes. Differences in eye size can be observed even between closely related individuals, yet we understand little about how this affects vision.
Gavin J Taylor, Pierre Tichit, Marie D Schmidt, Andrew J Bodey, Christoph Rau, Emily Baird   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Evaluation of Non-Spherical Particle Models for Mineral Dust in Multi-Wavelength Polarization Lidar Applications: Comparison of Spheroid, Super-Ellipsoid, and Irregular-Hexagonal Models

Remote Sensing
Mineral dust aerosols play an important role in the Earth’s radiation budget and climate system, and their optical properties strongly influence the accuracy of polarization lidar retrievals. Developing realistic optical models is therefore essential for
Laibin Wang, Dong Liu
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source