Results 21 to 30 of about 4,933,247 (258)
Network resilience in future optical networks
, 2009 Network resilience is an issue of deep concern to network operators being eager to deploy high-capacity fibre networks, since a single failure in the network could result in significant losses of revenue.
Ilse Lievens +39 more
core +1 more source
Investigation of performance issues affecting optical circuit and packet switched WDM networks [PDF]
, 2009 Optical switching represents the next step in the evolution of optical networks. This thesis describes work that was carried out to examine performance issues which can occur in two distinct varieties of optical switching networks.
Smyth, Frank
core +2 more sources
Transparency in optical networks
, 2022 This paper deals with some aspects of optical networking technology which are expected to play a key role in future photonic networks. The guiding crossconnect designs and underlying generic architectures are addressed, with special emphasis on ...
Vathke, J., Foisel, H.-M., Strebel, B.
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
3R regeneration for all-optical networks
, 2022 S.333-337Optical signal regeneration is a key function needed for scalable all-optical networks. In this paper functional building blocks and schemes for all-optical 3R regeneration (Re-amplification, Re-shaping, Re-timing) are presented.
Sartorius, B.
core +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Investigation of the tolerance of wavelength-routed optical networks to traffic load variations. [PDF]
, 2006 This thesis focuses on the performance of circuit-switched wavelength-routed optical network with unpredictable traffic pattern variations. This characteristic of optical networks is termed traffic forecast tolerance.
Lao, Ningning, Lao, N.
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source