Results 71 to 80 of about 579,349 (293)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
IEEE Photonics Journal, 2017 In this paper, we propose and experimentally demonstrate an optical self-interference cancellation (OSIC) system with baseband predistortion for wideband over-the-air in-band full-duplex (IBFD) communication.
Yunhao Zhang +5 more
doaj +1 more source
Quantum Communication Network Utilizing Quadripartite Entangled States of Optical Field [PDF]
, 2009 We propose two types of quantum dense coding communication networks with optical continuous variables, in which a quadripartite entangled state of the optical field with totally three-party correlations of quadrature amplitudes is utilized.
C. E. Shannon +4 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Nanosecond channel-switching exact optical frequency synthesizer using an optical injection phase-locked loop (OIPLL) [PDF]
, 2004 Experimental results are reported on an optical frequency synthesizer for use in dynamic dense wavelength-division-multiplexing networks, based on a tuneable laser in an optical injection phase-locked loop for rapid wavelength locking.
Bayvel, P +6 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Spectral Efficiency Improved 2D-PAM8 Trellis Coded Modulation for Short Reach Optical System
IEEE Photonics Journal, 2017 This paper proposes and demonstrates a 31.25 Gbps two-dimensional eight level pulse amplitude modulation with trellis coded modulation (2D-PAM8-TCM) transmission in intensity modulation and direct detection based short reach system. In this system,
Yan Fu +5 more
doaj +1 more source
Topological protection of continuous frequency entangled biphoton states
Nanophotonics, 2021 Topological quantum optics that manipulates the topological protection of quantum states has attracted special interests in recent years. Here we demonstrate valley photonic crystals implementing topologically protected transport of the continuous ...
Jiang Zhen +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source