Results 61 to 70 of about 7,172 (218)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

High Sensitivity Refractometer Based on TiO2-Coated Adiabatic Tapered Optical Fiber via ALD Technology

Sensors, 2016
Atomic layer deposition (ALD) technology is introduced to fabricate a high sensitivity refractometer based on an adiabatic tapered optical fiber. Different thicknesses of titanium dioxide (TiO2) nanofilm were coated around the tapered fiber precisely and
Shan Zhu, Fufei Pang, Sujuan Huang, Fang Zou, Qiang Guo, Jianxiang Wen, Tingyun Wang   +6 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

System Performance Optimization of Frequency-Swept Pump-Based Rectangular Brillouin Optical Filter

IEEE Photonics Journal, 2017
In this paper, we realize a series of 2-GHz wide rectangular optical filters based on the stimulated Brillouin scattering (SBS) effect in optical fiber with a frequency-swept pump and gain feedback compensation scheme.
M. Shi, L. Yi, W. Wei, G. Pu, W. Hu
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

High-coherence parallelization in integrated photonics

Nature Communications
Coherent optics has profoundly impacted diverse applications ranging from communications, LiDAR to quantum computations. However, developing coherent systems in integrated photonics comes at great expense in hardware integration and energy efficiency ...
Xuguang Zhang, Zixuan Zhou, Yijun Guo, Minxue Zhuang, Warren Jin, Bitao Shen, Yujun Chen, Jiahui Huang, Zihan Tao, Ming Jin, Ruixuan Chen, Zhangfeng Ge, Zhou Fang, Ning Zhang, Yadong Liu, Pengfei Cai, Weiwei Hu, Haowen Shu, Dong Pan, John E. Bowers, Xingjun Wang, Lin Chang   +21 more
doaj   +1 more source

Significantly High Modulation Efficiency of Compact Graphene Modulator Based on Silicon Waveguide

Scientific Reports, 2018
We theoretically and experimentally demonstrate a significantly large modulation efficiency of a compact graphene modulator based on a silicon waveguide using the electro refractive effect of graphene.
Haowen Shu, Zhaotang Su, Le Huang, Zhennan Wu, Xingjun Wang, Zhiyong Zhang, Zhiping Zhou   +6 more
doaj   +1 more source

Flexible Baseband-Unit Aggregation Enabled by Reconfigurable Multi-IF Over WDM Fronthaul

IEEE Photonics Journal, 2018
In cloud-radio access network, baseband-unit (BBU) aggregation schemes have been intensively discussed to improve the efficiency of resources in light traffic times.
Haiyun Xin, Hao He, Kuo Zhang, Syed Baqar Hussain, Weisheng Hu   +4 more
doaj   +1 more source