Results 41 to 50 of about 7,242,720 (244)

All-Optical Assay to Study Biological Neural Networks

Frontiers in Neuroscience, 2018
We introduce a novel all-optical assay for functional studies of biological neural networks in vitro. We created a novel optogenetic construct named OptoCaMP which is a combination of a channelrhodopsin variant (CheRiff) and a red genetically encoded ...
Wardiya Afshar Saber, Federico M. Gasparoli, Marjet G. Dirks, Frank J. Gunn-Moore, Maciej Antkowiak   +4 more
doaj   +1 more source

Non-Volatile Reconfigurable Optical Digital Diffractive Neural Network Based on Phase Change Material

IEEE Photonics Journal
Optical diffractive neural networks have sparked extensive research due to their low power consumption and high-speed capabilities in image processing.
Qiaomu Hu, Jingyu Zhao, Chu Wu, Rui Zeng, Xiaobing Zhou, Shuang Zheng, Minming Zhang   +6 more
doaj   +1 more source

The role of all-optical neural networks

CoRR, 2023
In light of recent achievements in optical computing and machine learning, we consider the conditions under which all-optical computing may surpass electronic and optoelectronic computing in terms of energy efficiency and scalability. When considering the performance of a system as a whole, the cost of memory access and data acquisition is likely to be
Michal Matuszewski, Adam Prystupiuk, Andrzej Opala   +2 more
openaire   +3 more sources

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Translation-invariant optical neural network for image classification

Scientific Reports, 2022
The classification performance of all-optical Convolutional Neural Networks (CNNs) is greatly influenced by components’ misalignment and translation of input images in the practical applications.
Hoda Sadeghzadeh, Somayyeh Koohi
doaj   +1 more source

Multi-Functional Optical Spectrum Analysis Using Multi-Task Cascaded Neural Networks

IEEE Photonics Journal, 2022
In the optical communication systems, the optical spectrum (OS) provides useful informations for optical performance monitoring and optical link diagnosis.
Haoyu Wang, Sheng Cui, Changjian Ke, Chenglong Yu, Zi Liang, Deming Liu   +5 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

All-Optical Buffering Using Laser Neural Networks [PDF]

, 2003
We demonstrate an all-optical buffering method that can handle contention of three optical packets. We have employed a laser neural network as an all-optical arbiter that decides whether packet contention takes place.
Hill, M.T., Liu, Y., Hill, MT Martin, G. D. Khoe, Waardt, H Hugo = Huug de, H. J. S. Dorren, M. T. Hill, Liu, Y Yong, H. De Waardt, H.J.S. Dorren, Waardt, de, H., Y. Liu, Khoe, GD Giok-Djan, Khoe, G.D., Dorren, HJS Harm, G.D. Khoe, Dorren, H.J.S., M.T. Hill, Liu Student Member, Y. Liu   +19 more
core   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source