Results 61 to 70 of about 3,887,393 (242)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Theoretical investigation of measuring cerebral blood flow in the adult human head using bolus indocyanine green injection and near-infrared spectroscopy [PDF]

, 2007
To investigate the accuracy of measuring cerebral blood flow (CBF) using a bolus injection of indocyanine green (ICG) detected by near infrared spectroscopy in adult human heads, simulations were performed using a two layered model, representing the ...
Tachtsidis, I, Tachtsidis, I., Delpy, D., Tisdall, M, Leung, T., Smith, M., Elwell, CE, Elwell, C., Delpy, DT, Tisdall, M., Leung, TS, Smith, M   +11 more
core  

Molecular Interaction of a New Antibacterial Polymer with a Supported Lipid Bilayer Measured by an in situ Label-Free Optical Technique [PDF]

, 2013
The interaction of the antibacterial polymer–branched poly(ethylene imine) substituted with quaternary ammonium groups, PEO and alkyl chains, PEI25QI5J5A815–with a solid supported lipid bilayer was investigated using surface sensitive optical waveguide ...
Éva Kiss, Horváth, Róbert, Kobzi, Balázs, Robert Horvath, Helmut Keul, Balázs Kobzi, Martin Moeller, Keul, Helmut, Kiss, Éva, Möller, Martin, Balázs, Kobzi, Helmut, Keul, Martin, Moeller, Robert, Horvath, Éva, Kiss   +14 more
core   +1 more source

High sensitivity wide range ethanol concentration measurements in ethanol blended petrol using weakly tilted fiber Bragg grating

Discover Sensors
Due to worldwide increasing interest towards usage of bio-ethanol blended fuel, high accuracy measurement of ethanol content in ethanol blended petrol (EBP) is of high importance for fuel quality assurance. In the present work, we report high sensitivity
P. K. Saini, J. Kumar, O. Prakash
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

A recipe for near infrared spectroscopy and diffuse correlation spectroscopy phantoms with tunable optical and dynamic properties [PDF]

, 2018
We present a recipe of combined liquid phantoms for diffuse correlation spectroscopy and near-infrared spectroscopy with well-defined and easily tunable optical and dynamic ...
Spinelli L., Pifferi A., Cortese L., Pagliazzi M., Marta Zanoletti, Dalla Mora A., Antonio Pifferi, Marco Pagliazzi, Lo Presti G., Durduran T., Giuseppe Lo Presti, Davide Contini, Turgut Durduran, Taroni P., Weigel U., Lorenzo Cortese, Paola Taroni, Sanathana Konugolu Venkata Sekar, Udo M. Weigel, Zanoletti M., Alberto Dalla Mora, Contini D., Konugolu Venkata Sekar S., Lorenzo Spinelli, Taroni P, Pifferi A, Konugolu Venkata Sekar S, Weigel U, Dalla Mora A, Contini D, Lo Presti G, Cortese L, Zanoletti M, Spinelli L, Durduran T, Pagliazzi M   +35 more
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Phantoms for performance assessment of optical coherence tomography systems [PDF]

, 2012
In this paper, we describe the procedures to make epoxy resin and agarose phantoms designed using Mie scattering calculations. The phantoms are constructed to be used in the estimation of point spread function (PSF) of an optical coherence tomography ...
S. A. Hojjatoleslami, Corr, S.A., Podoleanu, A.G., Price, M.C., Podoleanu, Adrian Gh., Avanaki, M.R.N., Avanaki, Mohammad R.N., Mazrae Khoshki, R., Mark C. Price, Rohollah Mazraeh Khoshki, Price, Mark C., Adrian G. Podoleanu, Mohammad R. N. Avanaki, Corr, Serena A., Khoshki, Rohollah Mazraeh, Serena A. Corr, Hojjatoleslami, S.A.   +16 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source