Results 81 to 90 of about 4,168,716 (386)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

All-optical phase shifter and switch near 1550nm using tungsten disulfide (WS2) deposited tapered fiber. [PDF]

open access: yesOptics Express, 2016
All-optical phase shifters and switches play an important role for various all-optical applications including all-optical signal processing, sensing and communication.
Kan Wu   +5 more
semanticscholar   +1 more source

Slow light in molecular aggregates nanofilms [PDF]

open access: yes, 2011
We study slow light performance of molecular aggregates arranged in nanofilms by means of coherent population oscillations (CPO). The molecular cooperative behavior inside the aggregate enhances the delay of input signals in the GHz range in comparison ...
E. Cabrera-Granado   +3 more
core   +3 more sources

Germline variants in CDKN2A wild‐type melanoma prone families

open access: yesMolecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen   +5 more
wiley   +1 more source

A Review of Silicon‐Based Integrated Optical Switches

open access: yesLaser & Photonics Reviews, 2023
Recently, silicon‐integrated optical circuits have attracted intensive interests, thanks to the compatibility with the complementary metal‐oxide‐semiconductor (CMOS) technology that enables mass production at low cost.
Xiaojun Chen, Jiao Lin, Ke Wang
semanticscholar   +1 more source

MEMS optical switch: Switching time reduction

open access: yesOpen Computer Science, 2016
Existing 3D MEMS-based optical switches offer good optical properties (low insertion loss, low crosstalk), high reliability and low power consumption.
Plander Ivan, Stepanovsky Michal
doaj   +1 more source

All-optical pulse reshaping and retiming systems incorporating pulse shaping fiber Bragg grating

open access: yes, 2006
This paper demonstrates two optical pulse retiming and reshaping systems incorporating superstructured fiber Bragg gratings (SSFBGs) as pulse shaping elements.
Ibsen, M.   +3 more
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

All-Optical Switch Based on a Fiber-Chip-Fiber Opto-Mechanical System With Ultrahigh Extinction Ratio

open access: yesIEEE Photonics Journal, 2017
We propose and experimentally demonstrate an all-optical switch based on a fiber-chip-fiber opto-mechanical system driven by thermal radiation. The two optical fibers are both designed as movable cantilever structures with a free-hanging length.
Li Liu, Jin Yue, Zhihua Li
doaj   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

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