Results 21 to 30 of about 61,825 (218)

Bacterial chemotaxis in an optical trap. [PDF]

open access: yesPLoS ONE, 2011
An optical trapping technique is implemented to investigate the chemotactic behavior of a marine bacterial strain Vibrio alginolyticus. The technique takes the advantage that the bacterium has only a single polar flagellum, which can rotate either in the
Tuba Altindal   +2 more
doaj   +1 more source

Chirality in Optical Trapping and Optical Binding

open access: yesPhotonics, 2015
Optical trapping is a well-established technique that is increasingly used on biological substances and nanostructures. Chirality, the property of objects that differ from their mirror image, is also of significance in such fields, and a subject of much ...
David S. Bradshaw   +3 more
doaj   +1 more source

Autler–Townes splitting in the trap-loss fluorescence spectroscopy due to single-step direct Rydberg excitation of cesium cold atomic ensemble

open access: yesAIP Advances, 2023
We experimentally investigate trap-loss spectra of the cesium 6S1/2(F = 4) → 71P3/2 Rydberg transition by combining the cesium atomic magneto-optical trap with the narrow-linewidth, continuously tunable 318.6 nm ultraviolet laser. Specifically, the atoms
Xin Wang   +8 more
doaj   +1 more source

Features of a Gaussian beam near-field diffraction upon variations in the relief height of subwavelength silicon optical elements

open access: yesКомпьютерная оптика, 2023
Features of the near-field diffraction of Gaussian beams and Laguerre-Gauss modes by silicon subwavelength optical elements with varying relief height were studied in this paper using a finite-difference time-domain method.
D.A. Savelyev
doaj   +1 more source

Particle Manipulation by Optical Forces in Microfluidic Devices

open access: yesMicromachines, 2018
Since the pioneering work of Ashkin and coworkers, back in 1970, optical manipulation gained an increasing interest among the scientific community. Indeed, the advantages and the possibilities of this technique are unsubtle, allowing for the manipulation
Petra Paiè   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Modeling Brownian Microparticle Trajectories in Lab-on-a-Chip Devices with Time Varying Dielectrophoretic or Optical Forces

open access: yesMicromachines, 2021
Lab-on-a-chip (LOC) devices capable of manipulating micro/nano-sized samples have spurred advances in biotechnology and chemistry. Designing and analyzing new and more advanced LOCs require accurate modeling and simulation of sample/particle dynamics ...
Mohammad Asif Zaman   +5 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Bidirectional helical motility of cytoplasmic dynein around microtubules

open access: yeseLife, 2014
Cytoplasmic dynein is a molecular motor responsible for minus-end-directed cargo transport along microtubules (MTs). Dynein motility has previously been studied on surface-immobilized MTs in vitro, which constrains the motors to move in two dimensions ...
Sinan Can, Mark A Dewitt, Ahmet Yildiz
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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