Results 61 to 70 of about 2,483,046 (293)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Modeling Brownian Microparticle Trajectories in Lab-on-a-Chip Devices with Time Varying Dielectrophoretic or Optical Forces

Micromachines, 2021
Lab-on-a-chip (LOC) devices capable of manipulating micro/nano-sized samples have spurred advances in biotechnology and chemistry. Designing and analyzing new and more advanced LOCs require accurate modeling and simulation of sample/particle dynamics ...
Mohammad Asif Zaman, Mo Wu, Punnag Padhy, Michael A. Jensen, Lambertus Hesselink, Ronald W. Davis   +5 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Broadband Backhaul Communication for Stratospheric Platforms: The Stratospheric Optical Payload Experiment (STROPEX) [PDF]

, 2006
A high bitrate optical downlink was performed by the stratospheric optical payload experiment (STROPEX), a part of the EU CAPANINA project. The STROPEX objectives were to design and build the necessary hardware to demonstrate an optical backhaul downlink
Knapek, Markus, Markus Knapek, Martin Brechtelsbauer, Joachim Horwath, Horwath, Joachim, Wilkerson, Brandon, Brandon Wilkerson, Brechtelsbauer, Martin, Bernhard Epple, Epple, Bernhard   +9 more
core   +1 more source

Hybrid Paul-optical trap with large optical access for levitated optomechanics

Physical Review Research
We present a hybrid trapping platform that allows us to levitate a charged nanoparticle in high vacuum using either optical fields, radio-frequency fields, or a combination thereof.
Eric Bonvin, Louisiane Devaud, Massimiliano Rossi, Andrei Militaru, Lorenzo Dania, Dmitry S. Bykov, Markus Teller, Tracy E. Northup, Lukas Novotny, Martin Frimmer   +9 more
doaj   +1 more source

The trapping and detection of single atoms using a spherical mirror

New Journal of Physics, 2012
We fabricate a miniature spherical mirror for tightly focusing an optical dipole trap for neutral atoms. The mirror formation process is modelled to predict the dimensions for particular fabrication parameters.
Arpan Roy, Andrew Bah Shen Jing, Murray D Barrett   +2 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Optical Binding Phenomena: Observations and Mechanisms [PDF]

, 2009
Novel results on the optical binding of optically-trapped micro-particles are presented. A sophisticated Mie scattering model is developed, capable of performing time-evolution simulations of a multi-particle system. This is used to analyse and interpret
TAYLOR, JONATHAN,MIDGLEY
core  

Design and Implementation of a Sun Outage Simulation System with High Uniformity and Stray Light Suppression Capability

Sensors
To enable accurate evaluation of satellite laser communication terminals under solar outage interference, this paper presents the design and implementation of a solar radiation simulation system targeting the 1540–1560 nm communication band.
Zhen Mao, Zhaohui Li, Yong Liu, Limin Gao, Jianke Zhao   +4 more
doaj   +1 more source

Integrated optical dipole trap for cold neutral atoms with an optical waveguide coupler

New Journal of Physics, 2013
An integrated optical dipole trap uses two-color (red and blue-detuned) traveling evanescent wave fields for trapping cold neutral atoms. To achieve longitudinal confinement, we propose using an integrated optical waveguide coupler, which provides a ...
J Lee, D H Park, S Mittal, M Dagenais, S L Rolston   +4 more
doaj   +1 more source