Results 101 to 110 of about 581,869 (300)

Computational toolbox for optical tweezers in geometrical optics

, 2014
Optical tweezers have found widespread application in many fields, from physics to biology. Here, we explain in detail how optical forces and torques can be described within the geometrical optics approximation and we show that this approximation ...
Callegari, Agnese, Gököz, A. Burak, Mijalkov, Mite, Volpe, Giovanni   +3 more
core   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

A Novel Joint Denoising Strategy for Coherent Doppler Wind Lidar Signals

Remote Sensing
Coherent Doppler Wind Lidar (CDWL) is an effective tool for measuring the atmospheric wind field. However, CDWL is affected by various noises, which can reduce the usable value of the received echo signal.
Yuefeng Zhao, Wenkai Song, Nannan Hu, Xue Zhou, Jiankang Luo, Jinrun Huang, Qianqian Tao   +6 more
doaj   +1 more source

Metasurface Optics for Full-color Computational Imaging

, 2018
Conventional imaging systems comprise large and expensive optical components which successively mitigate aberrations. Metasurface optics offers a route to miniaturize imaging systems by replacing bulky components with flat and compact implementations ...
Colburn, Shane, Majumdar, Arka, Zhan, Alan   +2 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Bidirectional Propagation Properties of Partially Coherent Laguerre–Gaussian Beams in Atmospheric Turbulence and Plasma

Photonics
The bidirectional propagation properties of partially coherent Laguerre–Gaussian (PCLG) beams under atmospheric turbulence and plasma were numerically investigated.
Yuelei Zhang, Linxuan Yao, Yuanhao Zhao, Hui Zhang, Yangjian Cai, Yangsheng Yuan, Yaru Gao   +6 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Cartographic distortions make dielectric spacetime analog models imperfect mimickers

, 2016
It is commonly assumed that if the optical metric of a dielectric medium is identical to the metric of a vacuum space-time then light propagation through the dielectric mimics light propagation in the vacuum.
Fathi, Mohsen, Thompson, Robert T.
core   +1 more source