Results 81 to 90 of about 584,393 (295)

Light bullets in optical tandems [PDF]

Optics Letters, 2009
We address the concept of three-dimensional light bullet formation in structures where nonlinearity and dispersion are contributed by different materials, including metamaterials, which are used at their best to create suitable conditions where bullets can form.
Torner Sabata, Lluís, Kartashov, Yaroslav V.   +1 more
openaire   +5 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Light ray modulation controls optical system alignment [PDF]

, 1965
Light ray modulator maintains focus in optical system subject to severe thermal gradients, vibration and shock.

core   +1 more source

Low-light-level nonlinear optics with slow light

, 2003
Electromagnetically induced transparency in an optically thick, cold medium creates a unique system where pulse-propagation velocities may be orders of magnitude less than $c$ and optical nonlinearities become exceedingly large.
A. Furusawa, A. Kuzmich, A.S. Zibrov, C.G. Townsend, C.H. van der Wal, Carlo Ottaviani, Danielle A. Braje, David Petrosyan, G. Y. Yin, H. Schmidt, J.P. Marangos, L.-M. Duan, L.V. Hau, M. Prevedelli, M.D. Lukin, M.D. Lukin, Mattias T. Johnsson, Michael Kash, Min Yan, Phillips, S. E. Harris, S.E. Harris, S.E. Harris, S.E. Harris, Vlatko Balić, Wolfgang Ketterle, Ying-Cheng Chen   +26 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Optical scatter of quantum noise filter cavity optics

, 2015
Optical cavities to filter squeezed light for quantum noise reduction require optics with very low scattering losses. We report on measured light scattering from two super-polished fused silica optics before and after applying highly-reflective ion-beam ...
Amra, Claude, Lequime, Michel, Magaña-Sandoval, Fabian, Smith, Joshua R., Vander-Hyde, Daniel, Zerrad, Myriam   +5 more
core   +3 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Evolution of the Phase Singularity of an Orbital Angular Momentum Beam with an Astigmatism Phase

Photonics
In this study, we explore the impact of the astigmatism phase on the evolution of the phase singularity of an orbital angular momentum (OAM) beam propagating through free space. The results demonstrate that the high-order phase singularity dispersed into
Chunhao Liang, Cuiling Zheng, Xinru Lian, Qian Chen, Yaru Gao, Jinsong Liu, Yangjian Cai, Jun Zeng   +7 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source