Results 41 to 50 of about 134,221 (268)

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Residual channel attention based sample adaptation few-shot learning for hyperspectral image classification

Scientific Reports
Few-shot learning (FSL) uses prior knowledge and supervised experience to effectively classify hyperspectral images (HSIs), thereby reducing the cost of large numbers of labeled samples.
Yuefeng Zhao, Jingqi Sun, Nannan Hu, Chengmin Zai, Yanwei Han   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Dual-mode varifocal Moiré metalens for quantitative phase and edge-enhanced imaging

Nanophotonics
Transport-of-intensity equation (TIE) as a noninterference method for quantitative phase imaging (QPI) has broad applications in micrographic imaging and optical metrology.
Lian Yi, Liu Yongqi, Cheng Dewen, Chi Cheng, Bao Yanjun, Wang Yongtian   +5 more
doaj   +1 more source

Dielectric broadband meta-vector-polarizers based on nematic liquid crystal

APL Photonics, 2017
Polarizer, as an indispensable optical element, has been widely used in various optical systems, which splits a beam into two beams of orthogonal linear polarizations. Due to the appearance of the vector optical field (VOF) and its unique properties, the
Gui-Geng Liu, Yun-Han Lee, Yuge Huang, Zheyuan Zhu, Guanjun Tan, Meng-Qiang Cai, Ping-Ping Li, Dan Wang, Yongnan Li, Shuo Pang, Chenghou Tu, Shin-Tson Wu, Hui-Tian Wang   +12 more
doaj   +1 more source

Light bullets in optical tandems [PDF]

Optics Letters, 2009
We address the concept of three-dimensional light bullet formation in structures where nonlinearity and dispersion are contributed by different materials, including metamaterials, which are used at their best to create suitable conditions where bullets can form.
Torner Sabata, Lluís, Kartashov, Yaroslav V.   +1 more
openaire   +5 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Propagation Properties of Partially Coherent Flat-Topped Beam Rectangular Arrays in Plasma and Atmospheric Turbulence

Photonics
Propagation properties represent a critical aspect of laser beams utilized in free space optical (FSO) communications. We examined the evolution characteristics of the electric field associated with partially coherent flat-topped beam rectangular arrays ...
Xinkai Ma, Hui Zhang, Yuanhao Zhao, LinXuan Yao, Changchun Yu, Yaru Gao, Yangsheng Yuan, Yangjian Cai, Bohan Guo   +8 more
doaj   +1 more source