Results 121 to 130 of about 1,208,254 (376)
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Cyclic Voltammetry and Micro-Raman Study of Graphene Oxide-Coated Silicon Substrates
CrystalsThis work presents the improvement of the electro-optical response of n-type crystalline silicon via dip-coated graphene oxide (GO) thin films. GO was deposited on Si/SiO2 by immersion, and the resulting heterostructures were characterized by cyclic ...
Grazia Giuseppina Politano
doaj +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Applied Optics, 2019 Starting from a peculiar image observed below a bubble that is floating at a water–air interface, this paper analyzes several optical properties of these special types of refracting objects (termed bubble axicons). Using mainly geometrical optics, their relation to common axicons, the shadow-sausage effect, and elementary optical catastrophes (caustics)
openaire +3 more sources
Optics-less smart sensors and a possible mechanism of cutaneous vision in nature
, 2008 Optics-less cutaneous (skin) vision is not rare among living organisms, though its mechanisms and capabilities have not been thoroughly investigated.
A. B. Sichert +17 more
core +1 more source
Molecular Oncology, EarlyView.Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo +11 more
wiley +1 more source
Exploiting Extraordinary Optical Transmission in Plasmonic Slit Nanoantennas for Sensor Applications
IEEE Photonics JournalIn this article, a plasmonic gold nanoantenna is proposed as a sensor to monitor refractive index variations between 1.30 and 1.35. These values are defined since they are characteristic of, for instance, water-based solutions, DNA, or haemoglobin.
Ricardo A. Marques Lameirinhas +4 more
doaj +1 more source
Pripravljenost slovenskih internetnih uporabnikov za priklop in plačilo za uporabo optičnega omrežja
Economic and Business Review, 2019 There is a lack of demand for next generation access (NGA) networks in both the EU and Slovenia. This paper examines the factors that influence the willingness to connect to and pay for the use of fibre optic networks, which are among the most ...
Matej Švigelj +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source