Results 31 to 40 of about 314,969 (268)

On Attainability of Optimal Solutions for Linear Elliptic Equations with Unbounded Coefficients

Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Modelûvannâ, 2011
We study an optimal boundary control problem (OCP) associated to a linear elliptic equation —div (Vj/ + A(x)Vy) = f describing diffusion in a turbulent flow. The characteristic feature of this equation is the fact that, in applications, the stream matrix
P. I. Kogut, O. P. Kupenko
doaj   +1 more source

On optimality conditions for optimal control problem in coefficients for Δ p -Laplacian [PDF]

Boundary Value Problems, 2014
The considered optimal control problem involves the minimization of a functional describing the discrepancy between the solution \(y\) of a nonlinear Dirichlet boundary value problem for the equation in the \(p\)-Laplacian \(\Delta_p(u,y)=f\) and \(y_d\), which is a given distribution. In this equation, \(u\) means the control and belongs to a class of
Rosanna Manzo, Olha P. Kupenko, Olha P. Kupenko   +2 more
openaire   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Resource Tuned Optimal Random Network Coding for Single Hop Multicast future 5G Networks [PDF]

International Journal of Electronics and Telecommunications, 2019
Optimal random network coding is reduced complexity in computation of coding coefficients, computation of encoded packets and coefficients are such that minimal transmission bandwidth is enough to transmit coding coefficient to the destinations and ...
Dhawa Sang Dong, Yagnya Murti Pokhrel, Anand Gachhadar, Ram Krishna Maharjan, Faizan Qamar, Iraj Sadegh Amiri   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

mploying Virial Coefficients for Optimal Solutions in Variational Calculations

Cumhuriyet Science Journal
In this study, virial coefficients for one and two-electron hydrogen and helium-like quantum dot structures confined in an infinite potential well were calculated.
Mahmut Özgür Sezer
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Asymptotic analysis of optimal control problems on the semiaxes for Carathéodory differential inclusions with fast oscillating coefficients

Nonlinear Analysis, 2023
We consider an optimal control problem for a differential inclusion of the Carathéodory type affine with respect to the control with a coercive cost functional on a semiaxis and with fast oscillating time-dependent coefficients.
Sergey Dashkovskiy, Oleksiy Kapustyan, Olena Kapustian, Tetyana Zhuk   +3 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source